The effect of topical 0.05% cyclosporine on recurrence following pterygium surgery
Ece Turan-Vural¹, Banu Torun-Acar¹, S Argun Kivanc², Suphi Acar¹¹Haydarpaşa Numune Education and Research Hospital, Ophthalmology Clinic, Istanbul, Turkey; ²Umranıye Education and Research Hospital, Ophthalmology Clinic, I...
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Dove Medical Press
2011
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oai:doaj.org-article:ec46a63564cd478c863f6f4736f5b4072021-12-02T07:42:51ZThe effect of topical 0.05% cyclosporine on recurrence following pterygium surgery1177-54671177-5483https://doaj.org/article/ec46a63564cd478c863f6f4736f5b4072011-06-01T00:00:00Zhttp://www.dovepress.com/the-effect-of-topical-005-cyclosporine-on-recurrence-following-pterygi-a7756https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Ece Turan-Vural¹, Banu Torun-Acar¹, S Argun Kivanc², Suphi Acar¹¹Haydarpaşa Numune Education and Research Hospital, Ophthalmology Clinic, Istanbul, Turkey; ²Umranıye Education and Research Hospital, Ophthalmology Clinic, Istanbul, TurkeyPurpose: To investigate the role of postoperative topical 0.05% cyclosporine A (CsA) eye drops (Restasis®, Allergan Pharmaceutical) in the prevention of recurrence among patients with primary pterygium treated with bare-sclera technique.Methods: In this prospective randomized controlled study, 36 eyes (34 patients) with primary pterygium were randomized into two groups: Group I comprised 18 eyes (18 patients), and Group II comprised 18 eyes (16 patients). Bare sclera technique was performed in both groups. In Group I, 0.05% CsA was administered postoperatively at 6-hour intervals for 6 months, and Group II did not receive any cyclosporine treatment. The patients were assessed for recurrence, side effects, and complications at postoperative 1 and 7 days as well as each month during the following year. Conjunctival advances which showed a limbus higher than 1 mm were recognized as recurrence.Results: Recurrence occurred in four patients (22.2%) in Group I and in eight (44.4%) patients in Group II.Conclusion: Postoperative application of low-dose CsA can be effective for preventing recurrences after primary pterygium surgery.Keywords: primary pterygium, cyclosporine A, bare scleraTuran-Vural ETorun-Acar BTKivanc SAAcar SDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 881-885 (2011) |
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DOAJ |
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DOAJ |
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EN |
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Ophthalmology RE1-994 |
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Ophthalmology RE1-994 Turan-Vural E Torun-Acar BT Kivanc SA Acar S The effect of topical 0.05% cyclosporine on recurrence following pterygium surgery |
| description |
Ece Turan-Vural¹, Banu Torun-Acar¹, S Argun Kivanc², Suphi Acar¹¹Haydarpaşa Numune Education and Research Hospital, Ophthalmology Clinic, Istanbul, Turkey; ²Umranıye Education and Research Hospital, Ophthalmology Clinic, Istanbul, TurkeyPurpose: To investigate the role of postoperative topical 0.05% cyclosporine A (CsA) eye drops (Restasis®, Allergan Pharmaceutical) in the prevention of recurrence among patients with primary pterygium treated with bare-sclera technique.Methods: In this prospective randomized controlled study, 36 eyes (34 patients) with primary pterygium were randomized into two groups: Group I comprised 18 eyes (18 patients), and Group II comprised 18 eyes (16 patients). Bare sclera technique was performed in both groups. In Group I, 0.05% CsA was administered postoperatively at 6-hour intervals for 6 months, and Group II did not receive any cyclosporine treatment. The patients were assessed for recurrence, side effects, and complications at postoperative 1 and 7 days as well as each month during the following year. Conjunctival advances which showed a limbus higher than 1 mm were recognized as recurrence.Results: Recurrence occurred in four patients (22.2%) in Group I and in eight (44.4%) patients in Group II.Conclusion: Postoperative application of low-dose CsA can be effective for preventing recurrences after primary pterygium surgery.Keywords: primary pterygium, cyclosporine A, bare sclera |
| format |
article |
| author |
Turan-Vural E Torun-Acar BT Kivanc SA Acar S |
| author_facet |
Turan-Vural E Torun-Acar BT Kivanc SA Acar S |
| author_sort |
Turan-Vural E |
| title |
The effect of topical 0.05% cyclosporine on recurrence following pterygium surgery |
| title_short |
The effect of topical 0.05% cyclosporine on recurrence following pterygium surgery |
| title_full |
The effect of topical 0.05% cyclosporine on recurrence following pterygium surgery |
| title_fullStr |
The effect of topical 0.05% cyclosporine on recurrence following pterygium surgery |
| title_full_unstemmed |
The effect of topical 0.05% cyclosporine on recurrence following pterygium surgery |
| title_sort |
effect of topical 0.05% cyclosporine on recurrence following pterygium surgery |
| publisher |
Dove Medical Press |
| publishDate |
2011 |
| url |
https://doaj.org/article/ec46a63564cd478c863f6f4736f5b407 |
| work_keys_str_mv |
AT turanvurale theeffectoftopical005cyclosporineonrecurrencefollowingpterygiumsurgery AT torunacarbt theeffectoftopical005cyclosporineonrecurrencefollowingpterygiumsurgery AT kivancsa theeffectoftopical005cyclosporineonrecurrencefollowingpterygiumsurgery AT acars theeffectoftopical005cyclosporineonrecurrencefollowingpterygiumsurgery AT turanvurale effectoftopical005cyclosporineonrecurrencefollowingpterygiumsurgery AT torunacarbt effectoftopical005cyclosporineonrecurrencefollowingpterygiumsurgery AT kivancsa effectoftopical005cyclosporineonrecurrencefollowingpterygiumsurgery AT acars effectoftopical005cyclosporineonrecurrencefollowingpterygiumsurgery |
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