Concise and scalable synthesis of (±)-phosphonothrixin

A concise and scalable method for the synthesis of (±)-phosphonothrixin (1), an herbicidal antibiotic containing a C–P bond, was developed. We developed a simpler and more responsible method for the synthetic precursor, epoxy alcohol 2. The synthetic route is efficient, requiring only six steps to i...

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Autores principales: Yoshitaka Matsushima, Koki Nakamura
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/ec4723d48c37437ab9e9599e3bf9f9cc
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