Prevention of immune nephritis by the small molecular weight immunomodulator iguratimod in MRL/lpr mice.

<h4>Objective</h4>This study was performed to investigate the therapeutic effects of iguratimod in a lupus mouse model.<h4>Methods</h4>Female MRL/lpr mice were treated with iguratimod, vehicle solution or cyclophosphamide. Proteinuria was monitored and kidney injury was blind...

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Autores principales: Qingran Yan, Fang Du, Xinfang Huang, Qiong Fu, Sheng Chen, Dai Dai, Chunde Bao
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/ec484e5589ca43fb8bbf01df96b8bc29
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