Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review

Ann D Colosia,1 Roberto Palencia,2 Shahnaz Khan1 1RTI Health Solutions, Research Triangle Park, NC, USA; 2Boehringer Ingelheim GmbH, Ingelheim, Germany Background: Hypertension and obesity are known to contribute, directly or indirectly, to the development of long-term complications of type 2 diabet...

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Autores principales:	Colosia AD, Palencia R, Khan S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/ec50eead186e4b7d8418c04356a5767b
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spelling	oai:doaj.org-article:ec50eead186e4b7d8418c04356a5767b2021-12-02T01:28:50ZPrevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review1178-7007https://doaj.org/article/ec50eead186e4b7d8418c04356a5767b2013-09-01T00:00:00Zhttp://www.dovepress.com/prevalence-of-hypertension-and-obesity-in-patients-with-type-2-diabete-a14378https://doaj.org/toc/1178-7007Ann D Colosia,1 Roberto Palencia,2 Shahnaz Khan1 1RTI Health Solutions, Research Triangle Park, NC, USA; 2Boehringer Ingelheim GmbH, Ingelheim, Germany Background: Hypertension and obesity are known to contribute, directly or indirectly, to the development of long-term complications of type 2 diabetes mellitus (T2DM). Knowing the prevalence of these comorbidities is important for determining the size of the population that may benefit from strategies that reduce blood pressure and weight while controlling blood glucose. Methods: In this systematic literature review, electronic searches of PubMed, Embase, and the Cochrane Library were conducted to identify observational studies of hypertension and/or obesity prevalence in patients with T2DM throughout the world. The searches were limited to studies reported in English from January 1, 2001 to February 16, 2012. Results: From a total of 2,688 studies, 92 observational studies provided prevalence rates for hypertension and/or obesity specifically in adults with T2DM. Fifteen studies of specific subtypes of hypertension or subpopulations with T2DM were subsequently excluded, leaving 78 studies (in 77 articles) for inclusion in this article. Of these, 61 studies reported hypertension prevalence, 44 reported obesity prevalence, and 12 reported the prevalence of hypertension with obesity. Most studies had a low risk of bias regarding diagnosis of T2DM (70/78), hypertension (59/69), or obesity (45/47). The continental regions with the most observational studies of hypertension or obesity prevalence were Europe (n = 30) and Asia (n = 26). Hypertension rates typically were high in all regions; most studies presented rates above 50%, and many presented rates above 75%. Obesity rates exceeded 30% in 38 of 44 studies and 50% in 14 of 44 studies, especially those assessing central obesity (based on waist circumference). Among obese adults, hypertension rates were at or above 70% in Asia and above 80% in Europe; rates were lower in North and South America but still above 30%. Conclusion: Around the world, hypertension and obesity, separately or together, are common comorbidities in adults with T2DM. Keywords: epidemiology, waist circumference, blood pressure, body mass index, T2DMColosia ADPalencia RKhan SDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2013, Iss default, Pp 327-338 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Colosia AD Palencia R Khan S Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review
description	Ann D Colosia,1 Roberto Palencia,2 Shahnaz Khan1 1RTI Health Solutions, Research Triangle Park, NC, USA; 2Boehringer Ingelheim GmbH, Ingelheim, Germany Background: Hypertension and obesity are known to contribute, directly or indirectly, to the development of long-term complications of type 2 diabetes mellitus (T2DM). Knowing the prevalence of these comorbidities is important for determining the size of the population that may benefit from strategies that reduce blood pressure and weight while controlling blood glucose. Methods: In this systematic literature review, electronic searches of PubMed, Embase, and the Cochrane Library were conducted to identify observational studies of hypertension and/or obesity prevalence in patients with T2DM throughout the world. The searches were limited to studies reported in English from January 1, 2001 to February 16, 2012. Results: From a total of 2,688 studies, 92 observational studies provided prevalence rates for hypertension and/or obesity specifically in adults with T2DM. Fifteen studies of specific subtypes of hypertension or subpopulations with T2DM were subsequently excluded, leaving 78 studies (in 77 articles) for inclusion in this article. Of these, 61 studies reported hypertension prevalence, 44 reported obesity prevalence, and 12 reported the prevalence of hypertension with obesity. Most studies had a low risk of bias regarding diagnosis of T2DM (70/78), hypertension (59/69), or obesity (45/47). The continental regions with the most observational studies of hypertension or obesity prevalence were Europe (n = 30) and Asia (n = 26). Hypertension rates typically were high in all regions; most studies presented rates above 50%, and many presented rates above 75%. Obesity rates exceeded 30% in 38 of 44 studies and 50% in 14 of 44 studies, especially those assessing central obesity (based on waist circumference). Among obese adults, hypertension rates were at or above 70% in Asia and above 80% in Europe; rates were lower in North and South America but still above 30%. Conclusion: Around the world, hypertension and obesity, separately or together, are common comorbidities in adults with T2DM. Keywords: epidemiology, waist circumference, blood pressure, body mass index, T2DM
format	article
author	Colosia AD Palencia R Khan S
author_facet	Colosia AD Palencia R Khan S
author_sort	Colosia AD
title	Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review
title_short	Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review
title_full	Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review
title_fullStr	Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review
title_full_unstemmed	Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review
title_sort	prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/ec50eead186e4b7d8418c04356a5767b
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Prevalence of hypertension and obesity in patients with type 2 diabetes mellitus in observational studies: a systematic literature review

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