Polycation-π interactions are a driving force for molecular recognition by an intrinsically disordered oncoprotein family.

Molecular recognition by intrinsically disordered proteins (IDPs) commonly involves specific localized contacts and target-induced disorder to order transitions. However, some IDPs remain disordered in the bound state, a phenomenon coined "fuzziness", often characterized by IDP polyvalency...

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Auteurs principaux: Jianhui Song, Sheung Chun Ng, Peter Tompa, Kevin A W Lee, Hue Sun Chan
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/ec57d0a2b316409cb04e42cf4687e376
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