Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells

Complex spike burst discharges of hippocampal neurons are proposed to be important for plasticity. Here, the authors report that in CA3 pyramidal neurons complex bursts generated by intrinsic mechanisms, can represent heterogeneous input-output functions and are regulated by HCN and Kv2 channels.

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Autores principales: Snezana Raus Balind, Ádám Magó, Mahboobeh Ahmadi, Noémi Kis, Zsófia Varga-Németh, Andrea Lőrincz, Judit K. Makara
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ec5ccf2302a34094ab1326a2f2915776
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spelling oai:doaj.org-article:ec5ccf2302a34094ab1326a2f29157762021-12-02T17:01:33ZDiverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells10.1038/s41467-019-09767-w2041-1723https://doaj.org/article/ec5ccf2302a34094ab1326a2f29157762019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09767-whttps://doaj.org/toc/2041-1723Complex spike burst discharges of hippocampal neurons are proposed to be important for plasticity. Here, the authors report that in CA3 pyramidal neurons complex bursts generated by intrinsic mechanisms, can represent heterogeneous input-output functions and are regulated by HCN and Kv2 channels.Snezana Raus BalindÁdám MagóMahboobeh AhmadiNoémi KisZsófia Varga-NémethAndrea LőrinczJudit K. MakaraNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Snezana Raus Balind
Ádám Magó
Mahboobeh Ahmadi
Noémi Kis
Zsófia Varga-Németh
Andrea Lőrincz
Judit K. Makara
Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells
description Complex spike burst discharges of hippocampal neurons are proposed to be important for plasticity. Here, the authors report that in CA3 pyramidal neurons complex bursts generated by intrinsic mechanisms, can represent heterogeneous input-output functions and are regulated by HCN and Kv2 channels.
format article
author Snezana Raus Balind
Ádám Magó
Mahboobeh Ahmadi
Noémi Kis
Zsófia Varga-Németh
Andrea Lőrincz
Judit K. Makara
author_facet Snezana Raus Balind
Ádám Magó
Mahboobeh Ahmadi
Noémi Kis
Zsófia Varga-Németh
Andrea Lőrincz
Judit K. Makara
author_sort Snezana Raus Balind
title Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells
title_short Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells
title_full Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells
title_fullStr Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells
title_full_unstemmed Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells
title_sort diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal ca3 pyramidal cells
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/ec5ccf2302a34094ab1326a2f2915776
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