Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells
Complex spike burst discharges of hippocampal neurons are proposed to be important for plasticity. Here, the authors report that in CA3 pyramidal neurons complex bursts generated by intrinsic mechanisms, can represent heterogeneous input-output functions and are regulated by HCN and Kv2 channels.
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Nature Portfolio
2019
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oai:doaj.org-article:ec5ccf2302a34094ab1326a2f29157762021-12-02T17:01:33ZDiverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells10.1038/s41467-019-09767-w2041-1723https://doaj.org/article/ec5ccf2302a34094ab1326a2f29157762019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09767-whttps://doaj.org/toc/2041-1723Complex spike burst discharges of hippocampal neurons are proposed to be important for plasticity. Here, the authors report that in CA3 pyramidal neurons complex bursts generated by intrinsic mechanisms, can represent heterogeneous input-output functions and are regulated by HCN and Kv2 channels.Snezana Raus BalindÁdám MagóMahboobeh AhmadiNoémi KisZsófia Varga-NémethAndrea LőrinczJudit K. MakaraNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Snezana Raus Balind Ádám Magó Mahboobeh Ahmadi Noémi Kis Zsófia Varga-Németh Andrea Lőrincz Judit K. Makara Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells |
description |
Complex spike burst discharges of hippocampal neurons are proposed to be important for plasticity. Here, the authors report that in CA3 pyramidal neurons complex bursts generated by intrinsic mechanisms, can represent heterogeneous input-output functions and are regulated by HCN and Kv2 channels. |
format |
article |
author |
Snezana Raus Balind Ádám Magó Mahboobeh Ahmadi Noémi Kis Zsófia Varga-Németh Andrea Lőrincz Judit K. Makara |
author_facet |
Snezana Raus Balind Ádám Magó Mahboobeh Ahmadi Noémi Kis Zsófia Varga-Németh Andrea Lőrincz Judit K. Makara |
author_sort |
Snezana Raus Balind |
title |
Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells |
title_short |
Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells |
title_full |
Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells |
title_fullStr |
Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells |
title_full_unstemmed |
Diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal CA3 pyramidal cells |
title_sort |
diverse synaptic and dendritic mechanisms of complex spike burst generation in hippocampal ca3 pyramidal cells |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/ec5ccf2302a34094ab1326a2f2915776 |
work_keys_str_mv |
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