Functional variation of SHP-2 promoter is associated with preterm birth and delayed myelination and motor development in preterm infants
Abstract Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutat...
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Main Authors: | , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Subjects: | |
Online Access: | https://doaj.org/article/ec5ff4c247af4a588c2fc76e7c4e4cc1 |
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