Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus
Abstract Nucleus pulposus (NP) cells reside in a physiologically hyperosmotic environment within the intervertebral disc. TonEBP/NFAT5 is an osmo-sensitive transcription factor that controls expression of genes critical for cell survival under hyperosmotic conditions. A recent report on NP and studi...
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Auteurs principaux: | Chao Liu, Hyowon Choi, Zariel I. Johnson, Jiwei Tian, Irving M. Shapiro, Makarand V. Risbud |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/ec6850c9958649eb86cff7b63c20bb32 |
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