Covalently-assembled single-chain protein nanostructures with ultra-high stability

De novo protein nanostructures are typically assembled via top-down approaches. Here, the authors developed a bottom-up approach, using split inteins to ligate multiple copies of a three-helix bundle to create 2D triangular and square-shaped structures with high stability.

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Auteurs principaux: Wenqin Bai, Cameron J. Sargent, Jeong-Mo Choi, Rohit V. Pappu, Fuzhong Zhang
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
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Accès en ligne:https://doaj.org/article/ec7cdad6dc2045c1b4932d232772c37b
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