Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases

Rajasekharreddy Pala,1,2 VT Anju,3 Madhu Dyavaiah,3 Siddhardha Busi,4 Surya M Nauli1,2 1Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA; 2Department of Medicine, University of California Irvine, Irvine, CA...

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Autores principales:	Pala R, Anju VT, Dyavaiah M, Busi S, Nauli SM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	cardiovascular diseases nanoscience nanoparticles nanomedicine nanocarriers treatment Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/ec7d102a161743fd97cb171439f43615
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spelling	oai:doaj.org-article:ec7d102a161743fd97cb171439f436152021-12-02T08:43:48ZNanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases1178-2013https://doaj.org/article/ec7d102a161743fd97cb171439f436152020-05-01T00:00:00Zhttps://www.dovepress.com/nanoparticle-mediated-drug-delivery-for-the-treatment-of-cardiovascula-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Rajasekharreddy Pala,1,2 VT Anju,3 Madhu Dyavaiah,3 Siddhardha Busi,4 Surya M Nauli1,2 1Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA; 2Department of Medicine, University of California Irvine, Irvine, CA 92868, USA; 3Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry, India; 4Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, IndiaCorrespondence: Rajasekharreddy Pala; Surya M Nauli Tel +714-516-5462; +714-516-5480Fax +714-516-5481Email rrpala@chapman.edu; nauli@chapman.eduAbstract: Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are not very useful, which demands promising alternative methods. Nanoscience and nanotechnology open a new window in the area of CVDs with an opportunity to achieve effective treatment, better prognosis, and less adverse effects on non-target tissues. The application of nanoparticles and nanocarriers in the area of cardiology has gathered much attention due to the properties such as passive and active targeting to the cardiac tissues, improved target specificity, and sensitivity. It has reported that more than 50% of CVDs can be treated effectively through the use of nanotechnology. The main goal of this review is to explore the recent advancements in nanoparticle-based cardiovascular drug carriers. This review also summarizes the difficulties associated with the conventional treatment modalities in comparison to the nanomedicine for CVDs.Keywords: cardiovascular diseases, nanoscience, nanoparticles, nanomedicine, nanocarriers, treatmentPala RAnju VTDyavaiah MBusi SNauli SMDove Medical Pressarticlecardiovascular diseasesnanosciencenanoparticlesnanomedicinenanocarrierstreatmentMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol Volume 15, Pp 3741-3769 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	cardiovascular diseases nanoscience nanoparticles nanomedicine nanocarriers treatment Medicine (General) R5-920
spellingShingle	cardiovascular diseases nanoscience nanoparticles nanomedicine nanocarriers treatment Medicine (General) R5-920 Pala R Anju VT Dyavaiah M Busi S Nauli SM Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
description	Rajasekharreddy Pala,1,2 VT Anju,3 Madhu Dyavaiah,3 Siddhardha Busi,4 Surya M Nauli1,2 1Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA; 2Department of Medicine, University of California Irvine, Irvine, CA 92868, USA; 3Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry, India; 4Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, IndiaCorrespondence: Rajasekharreddy Pala; Surya M Nauli Tel +714-516-5462; +714-516-5480Fax +714-516-5481Email rrpala@chapman.edu; nauli@chapman.eduAbstract: Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are not very useful, which demands promising alternative methods. Nanoscience and nanotechnology open a new window in the area of CVDs with an opportunity to achieve effective treatment, better prognosis, and less adverse effects on non-target tissues. The application of nanoparticles and nanocarriers in the area of cardiology has gathered much attention due to the properties such as passive and active targeting to the cardiac tissues, improved target specificity, and sensitivity. It has reported that more than 50% of CVDs can be treated effectively through the use of nanotechnology. The main goal of this review is to explore the recent advancements in nanoparticle-based cardiovascular drug carriers. This review also summarizes the difficulties associated with the conventional treatment modalities in comparison to the nanomedicine for CVDs.Keywords: cardiovascular diseases, nanoscience, nanoparticles, nanomedicine, nanocarriers, treatment
format	article
author	Pala R Anju VT Dyavaiah M Busi S Nauli SM
author_facet	Pala R Anju VT Dyavaiah M Busi S Nauli SM
author_sort	Pala R
title	Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_short	Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_full	Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_fullStr	Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_full_unstemmed	Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_sort	nanoparticle-mediated drug delivery for the treatment of cardiovascular diseases
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/ec7d102a161743fd97cb171439f43615
work_keys_str_mv	AT palar nanoparticlemediateddrugdeliveryforthetreatmentofcardiovasculardiseases AT anjuvt nanoparticlemediateddrugdeliveryforthetreatmentofcardiovasculardiseases AT dyavaiahm nanoparticlemediateddrugdeliveryforthetreatmentofcardiovasculardiseases AT busis nanoparticlemediateddrugdeliveryforthetreatmentofcardiovasculardiseases AT naulism nanoparticlemediateddrugdeliveryforthetreatmentofcardiovasculardiseases
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Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases

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