Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation

Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation

Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.

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Detalles Bibliográficos
Autores principales: Jemma Victoria Walker, Heng Zhuang, Donald Singer, Charlotte Sara Illsley, Wai Ling Kok, Kishor K. Sivaraj, Yan Gao, Chloe Bolton, Yuying Liu, Mengyuan Zhao, Portia Rebecca Clare Grayson, Shuang Wang, Jana Karbanová, Tim Lee, Stefano Ardu, Qingguo Lai, Jihui Liu, Moustapha Kassem, Shuo Chen, Kai Yang, Yuxing Bai, Christopher Tredwin, Alexander C. Zambon, Denis Corbeil, Ralf Adams, Basem M. Abdallah, Bing Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/ec84db5984804a3e870c585b51600d3f
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Descripción
Sumario:Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.

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