Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation

Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.

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Autores principales: Jemma Victoria Walker, Heng Zhuang, Donald Singer, Charlotte Sara Illsley, Wai Ling Kok, Kishor K. Sivaraj, Yan Gao, Chloe Bolton, Yuying Liu, Mengyuan Zhao, Portia Rebecca Clare Grayson, Shuang Wang, Jana Karbanová, Tim Lee, Stefano Ardu, Qingguo Lai, Jihui Liu, Moustapha Kassem, Shuo Chen, Kai Yang, Yuxing Bai, Christopher Tredwin, Alexander C. Zambon, Denis Corbeil, Ralf Adams, Basem M. Abdallah, Bing Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ec84db5984804a3e870c585b51600d3f
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spelling oai:doaj.org-article:ec84db5984804a3e870c585b51600d3f2021-12-02T15:35:11ZTransit amplifying cells coordinate mouse incisor mesenchymal stem cell activation10.1038/s41467-019-11611-02041-1723https://doaj.org/article/ec84db5984804a3e870c585b51600d3f2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11611-0https://doaj.org/toc/2041-1723Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.Jemma Victoria WalkerHeng ZhuangDonald SingerCharlotte Sara IllsleyWai Ling KokKishor K. SivarajYan GaoChloe BoltonYuying LiuMengyuan ZhaoPortia Rebecca Clare GraysonShuang WangJana KarbanováTim LeeStefano ArduQingguo LaiJihui LiuMoustapha KassemShuo ChenKai YangYuxing BaiChristopher TredwinAlexander C. ZambonDenis CorbeilRalf AdamsBasem M. AbdallahBing HuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jemma Victoria Walker
Heng Zhuang
Donald Singer
Charlotte Sara Illsley
Wai Ling Kok
Kishor K. Sivaraj
Yan Gao
Chloe Bolton
Yuying Liu
Mengyuan Zhao
Portia Rebecca Clare Grayson
Shuang Wang
Jana Karbanová
Tim Lee
Stefano Ardu
Qingguo Lai
Jihui Liu
Moustapha Kassem
Shuo Chen
Kai Yang
Yuxing Bai
Christopher Tredwin
Alexander C. Zambon
Denis Corbeil
Ralf Adams
Basem M. Abdallah
Bing Hu
Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation
description Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.
format article
author Jemma Victoria Walker
Heng Zhuang
Donald Singer
Charlotte Sara Illsley
Wai Ling Kok
Kishor K. Sivaraj
Yan Gao
Chloe Bolton
Yuying Liu
Mengyuan Zhao
Portia Rebecca Clare Grayson
Shuang Wang
Jana Karbanová
Tim Lee
Stefano Ardu
Qingguo Lai
Jihui Liu
Moustapha Kassem
Shuo Chen
Kai Yang
Yuxing Bai
Christopher Tredwin
Alexander C. Zambon
Denis Corbeil
Ralf Adams
Basem M. Abdallah
Bing Hu
author_facet Jemma Victoria Walker
Heng Zhuang
Donald Singer
Charlotte Sara Illsley
Wai Ling Kok
Kishor K. Sivaraj
Yan Gao
Chloe Bolton
Yuying Liu
Mengyuan Zhao
Portia Rebecca Clare Grayson
Shuang Wang
Jana Karbanová
Tim Lee
Stefano Ardu
Qingguo Lai
Jihui Liu
Moustapha Kassem
Shuo Chen
Kai Yang
Yuxing Bai
Christopher Tredwin
Alexander C. Zambon
Denis Corbeil
Ralf Adams
Basem M. Abdallah
Bing Hu
author_sort Jemma Victoria Walker
title Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation
title_short Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation
title_full Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation
title_fullStr Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation
title_full_unstemmed Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation
title_sort transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/ec84db5984804a3e870c585b51600d3f
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