Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation
Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.
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Nature Portfolio
2019
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oai:doaj.org-article:ec84db5984804a3e870c585b51600d3f2021-12-02T15:35:11ZTransit amplifying cells coordinate mouse incisor mesenchymal stem cell activation10.1038/s41467-019-11611-02041-1723https://doaj.org/article/ec84db5984804a3e870c585b51600d3f2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11611-0https://doaj.org/toc/2041-1723Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts.Jemma Victoria WalkerHeng ZhuangDonald SingerCharlotte Sara IllsleyWai Ling KokKishor K. SivarajYan GaoChloe BoltonYuying LiuMengyuan ZhaoPortia Rebecca Clare GraysonShuang WangJana KarbanováTim LeeStefano ArduQingguo LaiJihui LiuMoustapha KassemShuo ChenKai YangYuxing BaiChristopher TredwinAlexander C. ZambonDenis CorbeilRalf AdamsBasem M. AbdallahBing HuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019) |
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Science Q Jemma Victoria Walker Heng Zhuang Donald Singer Charlotte Sara Illsley Wai Ling Kok Kishor K. Sivaraj Yan Gao Chloe Bolton Yuying Liu Mengyuan Zhao Portia Rebecca Clare Grayson Shuang Wang Jana Karbanová Tim Lee Stefano Ardu Qingguo Lai Jihui Liu Moustapha Kassem Shuo Chen Kai Yang Yuxing Bai Christopher Tredwin Alexander C. Zambon Denis Corbeil Ralf Adams Basem M. Abdallah Bing Hu Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation |
description |
Mouse incisor growth depends upon mesenchymal stromal cells (MSCs) and transit amplifying cells (TACs). Here the authors describe a distinct population of MSCs that is maintained by TACs through Dlk1 ligand and that contribute to MTACs and mesenchymal lineages including dental pulp and odontoblasts. |
format |
article |
author |
Jemma Victoria Walker Heng Zhuang Donald Singer Charlotte Sara Illsley Wai Ling Kok Kishor K. Sivaraj Yan Gao Chloe Bolton Yuying Liu Mengyuan Zhao Portia Rebecca Clare Grayson Shuang Wang Jana Karbanová Tim Lee Stefano Ardu Qingguo Lai Jihui Liu Moustapha Kassem Shuo Chen Kai Yang Yuxing Bai Christopher Tredwin Alexander C. Zambon Denis Corbeil Ralf Adams Basem M. Abdallah Bing Hu |
author_facet |
Jemma Victoria Walker Heng Zhuang Donald Singer Charlotte Sara Illsley Wai Ling Kok Kishor K. Sivaraj Yan Gao Chloe Bolton Yuying Liu Mengyuan Zhao Portia Rebecca Clare Grayson Shuang Wang Jana Karbanová Tim Lee Stefano Ardu Qingguo Lai Jihui Liu Moustapha Kassem Shuo Chen Kai Yang Yuxing Bai Christopher Tredwin Alexander C. Zambon Denis Corbeil Ralf Adams Basem M. Abdallah Bing Hu |
author_sort |
Jemma Victoria Walker |
title |
Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation |
title_short |
Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation |
title_full |
Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation |
title_fullStr |
Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation |
title_full_unstemmed |
Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation |
title_sort |
transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/ec84db5984804a3e870c585b51600d3f |
work_keys_str_mv |
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