Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

The ExoY toxin is injected by Pseudomonas aeruginosainto host cells, where it is activated by an unknown host factor. Here the authors identify such factor as filamentous actin.

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Autores principales: Alexander Belyy, Dorothée Raoux-Barbot, Cosmin Saveanu, Abdelkader Namane, Vasily Ogryzko, Lina Worpenberg, Violaine David, Veronique Henriot, Souad Fellous, Christien Merrifield, Elodie Assayag, Daniel Ladant, Louis Renault, Undine Mechold
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/ec8ab7ad880b42b7a73e051cab8310c9
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spelling oai:doaj.org-article:ec8ab7ad880b42b7a73e051cab8310c92021-12-02T15:34:59ZActin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins10.1038/ncomms135822041-1723https://doaj.org/article/ec8ab7ad880b42b7a73e051cab8310c92016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13582https://doaj.org/toc/2041-1723The ExoY toxin is injected by Pseudomonas aeruginosainto host cells, where it is activated by an unknown host factor. Here the authors identify such factor as filamentous actin.Alexander BelyyDorothée Raoux-BarbotCosmin SaveanuAbdelkader NamaneVasily OgryzkoLina WorpenbergViolaine DavidVeronique HenriotSouad FellousChristien MerrifieldElodie AssayagDaniel LadantLouis RenaultUndine MecholdNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alexander Belyy
Dorothée Raoux-Barbot
Cosmin Saveanu
Abdelkader Namane
Vasily Ogryzko
Lina Worpenberg
Violaine David
Veronique Henriot
Souad Fellous
Christien Merrifield
Elodie Assayag
Daniel Ladant
Louis Renault
Undine Mechold
Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
description The ExoY toxin is injected by Pseudomonas aeruginosainto host cells, where it is activated by an unknown host factor. Here the authors identify such factor as filamentous actin.
format article
author Alexander Belyy
Dorothée Raoux-Barbot
Cosmin Saveanu
Abdelkader Namane
Vasily Ogryzko
Lina Worpenberg
Violaine David
Veronique Henriot
Souad Fellous
Christien Merrifield
Elodie Assayag
Daniel Ladant
Louis Renault
Undine Mechold
author_facet Alexander Belyy
Dorothée Raoux-Barbot
Cosmin Saveanu
Abdelkader Namane
Vasily Ogryzko
Lina Worpenberg
Violaine David
Veronique Henriot
Souad Fellous
Christien Merrifield
Elodie Assayag
Daniel Ladant
Louis Renault
Undine Mechold
author_sort Alexander Belyy
title Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
title_short Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
title_full Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
title_fullStr Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
title_full_unstemmed Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
title_sort actin activates pseudomonas aeruginosa exoy nucleotidyl cyclase toxin and exoy-like effector domains from martx toxins
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/ec8ab7ad880b42b7a73e051cab8310c9
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