$Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength$
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Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength

Georgios Labiris,1,2 Haris Sideroudi,2 Dimitris Angelonias,2 Kimonas Georgantzoglou,2 Vassilios P Kozobolis1,21Department of Ophthalmology, University Hospital of Alexandroupolis, 2Eye Institute of Thrace, Alexandroupolis, GreecePurpose: The aim of this study was to evaluate the impact of corneal cr...

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Autores principales:	Labiris G, Sideroudi H, Angelonias D, Georgantzoglou K, Kozobolis VP
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	keratoconus photorefractive keratectomy corneal cross linking blurring strength vector analysis Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/ec916f0ac43f466bb733841b3b8490eb
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spelling	oai:doaj.org-article:ec916f0ac43f466bb733841b3b8490eb2021-12-02T02:16:22ZImpact of corneal cross-linking combined with photorefractive keratectomy on blurring strength1177-5483https://doaj.org/article/ec916f0ac43f466bb733841b3b8490eb2016-04-01T00:00:00Zhttps://www.dovepress.com/impact-of-corneal-cross-linking-combined-with-photorefractive-keratect-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Georgios Labiris,1,2 Haris Sideroudi,2 Dimitris Angelonias,2 Kimonas Georgantzoglou,2 Vassilios P Kozobolis1,21Department of Ophthalmology, University Hospital of Alexandroupolis, 2Eye Institute of Thrace, Alexandroupolis, GreecePurpose: The aim of this study was to evaluate the impact of corneal cross-linking combined with photorefractive keratectomy (PRK) on blurring strength.Methods: A total of 63 patients with keratoconus were recruited for this study, and two study groups were formed according to the therapeutic intervention: corneal collagen cross-linking (CxL) group (33 patients) received corneal cross-linking according to the Dresden protocol, while the rest additionally received topography-guided photorefractive keratectomy (tCxL). The impact of surgical procedure on blurring strength was assessed by power vector analysis. Potential association between blurring strength and vision-specific quality of life was assessed using the National Eye Institute Visual Function Questionnaire (NEI-VFQ) 25 instrument.Results: Blurring strength presented excellent correlation with NEI-VFQ scores both preoperatively and postoperatively (all P<0.01). Both groups demonstrated nonsignificant changes in best-corrected visual acuity; however, only the tCxL group had significant reduction in blurring strength (13.48+10.86 [preoperative], 4.26+7.99 [postoperative], P=0.042).Conclusion: Only the combined treatment (tCxL) resulted in significant reduction in blurring strength. Moreover, the excellent correlation of blurring strength with NEI-VFQ scores indicates its reliability as an index of self-reported quality of life in keratoconus, since it seems to address the nonsignificant changes in best-corrected visual acuity following CxL treatments that are conceived as subjective improvement by the patient.Keywords: keratoconus, cornea crosslinking, blurring strength, tCxLLabiris GSideroudi HAngelonias DGeorgantzoglou KKozobolis VPDove Medical Pressarticlekeratoconusphotorefractive keratectomycorneal cross linkingblurring strengthvector analysisOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2016, Iss Issue 1, Pp 571-576 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	keratoconus photorefractive keratectomy corneal cross linking blurring strength vector analysis Ophthalmology RE1-994
spellingShingle	keratoconus photorefractive keratectomy corneal cross linking blurring strength vector analysis Ophthalmology RE1-994 Labiris G Sideroudi H Angelonias D Georgantzoglou K Kozobolis VP Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength
description	Georgios Labiris,1,2 Haris Sideroudi,2 Dimitris Angelonias,2 Kimonas Georgantzoglou,2 Vassilios P Kozobolis1,21Department of Ophthalmology, University Hospital of Alexandroupolis, 2Eye Institute of Thrace, Alexandroupolis, GreecePurpose: The aim of this study was to evaluate the impact of corneal cross-linking combined with photorefractive keratectomy (PRK) on blurring strength.Methods: A total of 63 patients with keratoconus were recruited for this study, and two study groups were formed according to the therapeutic intervention: corneal collagen cross-linking (CxL) group (33 patients) received corneal cross-linking according to the Dresden protocol, while the rest additionally received topography-guided photorefractive keratectomy (tCxL). The impact of surgical procedure on blurring strength was assessed by power vector analysis. Potential association between blurring strength and vision-specific quality of life was assessed using the National Eye Institute Visual Function Questionnaire (NEI-VFQ) 25 instrument.Results: Blurring strength presented excellent correlation with NEI-VFQ scores both preoperatively and postoperatively (all P<0.01). Both groups demonstrated nonsignificant changes in best-corrected visual acuity; however, only the tCxL group had significant reduction in blurring strength (13.48+10.86 [preoperative], 4.26+7.99 [postoperative], P=0.042).Conclusion: Only the combined treatment (tCxL) resulted in significant reduction in blurring strength. Moreover, the excellent correlation of blurring strength with NEI-VFQ scores indicates its reliability as an index of self-reported quality of life in keratoconus, since it seems to address the nonsignificant changes in best-corrected visual acuity following CxL treatments that are conceived as subjective improvement by the patient.Keywords: keratoconus, cornea crosslinking, blurring strength, tCxL
format	article
author	Labiris G Sideroudi H Angelonias D Georgantzoglou K Kozobolis VP
author_facet	Labiris G Sideroudi H Angelonias D Georgantzoglou K Kozobolis VP
author_sort	Labiris G
title	Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength
title_short	Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength
title_full	Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength
title_fullStr	Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength
title_full_unstemmed	Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength
title_sort	impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/ec916f0ac43f466bb733841b3b8490eb
work_keys_str_mv	AT labirisg impactofcornealcrosslinkingcombinedwithphotorefractivekeratectomyonblurringstrength AT sideroudih impactofcornealcrosslinkingcombinedwithphotorefractivekeratectomyonblurringstrength AT angeloniasd impactofcornealcrosslinkingcombinedwithphotorefractivekeratectomyonblurringstrength AT georgantzoglouk impactofcornealcrosslinkingcombinedwithphotorefractivekeratectomyonblurringstrength AT kozobolisvp impactofcornealcrosslinkingcombinedwithphotorefractivekeratectomyonblurringstrength
_version_	1718402628205936640

Impact of corneal cross-linking combined with photorefractive keratectomy on blurring strength

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