Infection by <named-content content-type="genus-species">Anaplasma phagocytophilum</named-content> Requires Recruitment of Low-Density Lipoprotein Cholesterol by Flotillins

ABSTRACT Anaplasma phagocytophilum is an obligatory intracellular bacterium that proliferates in membrane-bound inclusions. A. phagocytophilum is dependent on cholesterol and acquire cholesterol from low-density lipoprotein (LDL) endocytosed by mammalian host cells. The mechanism of cholesterol tran...

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Auteurs principaux: Qingming Xiong, Mingqun Lin, Weiyan Huang, Yasuko Rikihisa
Format: article
Langue:EN
Publié: American Society for Microbiology 2019
Sujets:
LDL
Accès en ligne:https://doaj.org/article/ec9217fa150944b9b7f29af6dd4a331e
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