Large-scale survey of prion protein genetic variability in scrapie disease-free goats from the United States.

Large-scale survey of prion protein genetic variability in scrapie disease-free goats from the United States.

Scrapie is a slowly progressive neurodegenerative disease of small ruminants caused by an accumulation of an abnormal isoform of prion protein in the central nervous system. Polymorphisms of the prion protein gene (PRNP) strongly modulate scrapie resistance and incubation period in goats. The aim of...

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Autores principales: Mohamed Zeineldin, Kimberly Lehman, Natalie Urie, Matthew Branan, Alyson Wiedenheft, Katherine Marshall, Suelee Robbe-Austerman, Tyler Thacker
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ec99e33d6cf549cc81aebfefa65b4440
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