Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast

Loss-of-function experiments are used in metabolic engineering to understand and optimise metabolism. Here, the authors apply auxin inducible protein degradation to test different metabolic engineering strategies for improved terpenoid production in yeast.

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Autores principales: Zeyu Lu, Bingyin Peng, Birgitta E. Ebert, Geoff Dumsday, Claudia E. Vickers
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ec9f52fb74584aa2b989e3d0bc618cc7
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spelling oai:doaj.org-article:ec9f52fb74584aa2b989e3d0bc618cc72021-12-02T14:03:51ZAuxin-mediated protein depletion for metabolic engineering in terpene-producing yeast10.1038/s41467-021-21313-12041-1723https://doaj.org/article/ec9f52fb74584aa2b989e3d0bc618cc72021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21313-1https://doaj.org/toc/2041-1723Loss-of-function experiments are used in metabolic engineering to understand and optimise metabolism. Here, the authors apply auxin inducible protein degradation to test different metabolic engineering strategies for improved terpenoid production in yeast.Zeyu LuBingyin PengBirgitta E. EbertGeoff DumsdayClaudia E. VickersNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zeyu Lu
Bingyin Peng
Birgitta E. Ebert
Geoff Dumsday
Claudia E. Vickers
Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast
description Loss-of-function experiments are used in metabolic engineering to understand and optimise metabolism. Here, the authors apply auxin inducible protein degradation to test different metabolic engineering strategies for improved terpenoid production in yeast.
format article
author Zeyu Lu
Bingyin Peng
Birgitta E. Ebert
Geoff Dumsday
Claudia E. Vickers
author_facet Zeyu Lu
Bingyin Peng
Birgitta E. Ebert
Geoff Dumsday
Claudia E. Vickers
author_sort Zeyu Lu
title Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast
title_short Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast
title_full Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast
title_fullStr Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast
title_full_unstemmed Auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast
title_sort auxin-mediated protein depletion for metabolic engineering in terpene-producing yeast
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ec9f52fb74584aa2b989e3d0bc618cc7
work_keys_str_mv AT zeyulu auxinmediatedproteindepletionformetabolicengineeringinterpeneproducingyeast
AT bingyinpeng auxinmediatedproteindepletionformetabolicengineeringinterpeneproducingyeast
AT birgittaeebert auxinmediatedproteindepletionformetabolicengineeringinterpeneproducingyeast
AT geoffdumsday auxinmediatedproteindepletionformetabolicengineeringinterpeneproducingyeast
AT claudiaevickers auxinmediatedproteindepletionformetabolicengineeringinterpeneproducingyeast
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