Genetic effects on longitudinal cognitive decline during the early stages of Alzheimer’s disease

Genetic effects on longitudinal cognitive decline during the early stages of Alzheimer’s disease

Abstract Cognitive decline in early-stage Alzheimer’s disease (AD) may depend on genetic variability. In the Swedish BioFINDER study, we used polygenic scores (PGS) (for AD, intelligence, and educational attainment) to predict longitudinal cognitive change (measured by mini-mental state examination...

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Autores principales: Atul Kumar, Maryam Shoai, Sebastian Palmqvist, Erik Stomrud, John Hardy, Niklas Mattsson-Carlgren, Oskar Hansson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/eca63dc7f9f04a0a98a3074419d85dc2
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