Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families

Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families

Abstract Protein disulfide isomerases (PDIs) support endoplasmic reticulum redox protein folding and cell-surface thiol-redox control of thrombosis and vascular remodeling. The family prototype PDIA1 regulates NADPH oxidase signaling and cytoskeleton organization, however the related underlying mech...

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Autores principales: Ana I. S. Moretti, Jessyca C. Pavanelli, Patrícia Nolasco, Matthias S. Leisegang, Leonardo Y. Tanaka, Carolina G. Fernandes, João Wosniak, Daniela Kajihara, Matheus H. Dias, Denise C. Fernandes, Hanjoong Jo, Ngoc-Vinh Tran, Ingo Ebersberger, Ralf P. Brandes, Diego Bonatto, Francisco R. M. Laurindo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ecacaa9b61b844f7b39828427de7b836
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