CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.

CCHCR1 is up-regulated in skin cancer and associated with EGFR expression.

Despite chronic inflammation, psoriatic lesions hardly ever progress to skin cancer. Aberrant function of the CCHCR1 gene (Coiled-Coil alpha-Helical Rod protein 1, HCR) within the PSORS1 locus may contribute to the onset of psoriasis. As CCHCR1 is expressed in certain cancers and regulates keratinoc...

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Autores principales: Sari Suomela, Outi Elomaa, Tiina Skoog, Risto Ala-aho, Leila Jeskanen, Jenita Pärssinen, Leena Latonen, Reidar Grénman, Juha Kere, Veli-Matti Kähäri, Ulpu Saarialho-Kere
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ecb05513a7f44388a05d1c369947f6b8
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