A rebinding-assay for measuring extreme kinetics using label-free biosensors

Abstract In vitro kinetic measurements allow mechanistic characterization of binding interactions and are particularly valuable throughout drug discovery, from confirmation of on-target binding in early discovery to fine-tuning of drug-binding properties in pre-clinical development. Early chemical m...

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Autor principal: John G. Quinn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ecb365e6b26849afba262a4b5282f867
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