Crosstalk between CST and RPA regulates RAD51 activity during replication stress

During replication stress, the RPA protein complex coats single-stranded DNA to preclude RAD51 loading. Here, the authors show how RPA and CST crosstalk to regulate RAD51 activity.

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Autores principales:	Kai-Hang Lei, Han-Lin Yang, Hao-Yen Chang, Hsin-Yi Yeh, Dinh Duc Nguyen, Tzu-Yu Lee, Xinxing Lyu, Megan Chastain, Weihang Chai, Hung-Wen Li, Peter Chi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ecb6eb4b3da245efbbff43e501310a5d
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spelling	oai:doaj.org-article:ecb6eb4b3da245efbbff43e501310a5d2021-11-08T11:12:52ZCrosstalk between CST and RPA regulates RAD51 activity during replication stress10.1038/s41467-021-26624-x2041-1723https://doaj.org/article/ecb6eb4b3da245efbbff43e501310a5d2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26624-xhttps://doaj.org/toc/2041-1723During replication stress, the RPA protein complex coats single-stranded DNA to preclude RAD51 loading. Here, the authors show how RPA and CST crosstalk to regulate RAD51 activity.Kai-Hang LeiHan-Lin YangHao-Yen ChangHsin-Yi YehDinh Duc NguyenTzu-Yu LeeXinxing LyuMegan ChastainWeihang ChaiHung-Wen LiPeter ChiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kai-Hang Lei Han-Lin Yang Hao-Yen Chang Hsin-Yi Yeh Dinh Duc Nguyen Tzu-Yu Lee Xinxing Lyu Megan Chastain Weihang Chai Hung-Wen Li Peter Chi Crosstalk between CST and RPA regulates RAD51 activity during replication stress
description	During replication stress, the RPA protein complex coats single-stranded DNA to preclude RAD51 loading. Here, the authors show how RPA and CST crosstalk to regulate RAD51 activity.
format	article
author	Kai-Hang Lei Han-Lin Yang Hao-Yen Chang Hsin-Yi Yeh Dinh Duc Nguyen Tzu-Yu Lee Xinxing Lyu Megan Chastain Weihang Chai Hung-Wen Li Peter Chi
author_facet	Kai-Hang Lei Han-Lin Yang Hao-Yen Chang Hsin-Yi Yeh Dinh Duc Nguyen Tzu-Yu Lee Xinxing Lyu Megan Chastain Weihang Chai Hung-Wen Li Peter Chi
author_sort	Kai-Hang Lei
title	Crosstalk between CST and RPA regulates RAD51 activity during replication stress
title_short	Crosstalk between CST and RPA regulates RAD51 activity during replication stress
title_full	Crosstalk between CST and RPA regulates RAD51 activity during replication stress
title_fullStr	Crosstalk between CST and RPA regulates RAD51 activity during replication stress
title_full_unstemmed	Crosstalk between CST and RPA regulates RAD51 activity during replication stress
title_sort	crosstalk between cst and rpa regulates rad51 activity during replication stress
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ecb6eb4b3da245efbbff43e501310a5d
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_version_	1718442388475609088

Crosstalk between CST and RPA regulates RAD51 activity during replication stress

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