Crosstalk between CST and RPA regulates RAD51 activity during replication stress

Crosstalk between CST and RPA regulates RAD51 activity during replication stress

During replication stress, the RPA protein complex coats single-stranded DNA to preclude RAD51 loading. Here, the authors show how RPA and CST crosstalk to regulate RAD51 activity.

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Autores principales: Kai-Hang Lei, Han-Lin Yang, Hao-Yen Chang, Hsin-Yi Yeh, Dinh Duc Nguyen, Tzu-Yu Lee, Xinxing Lyu, Megan Chastain, Weihang Chai, Hung-Wen Li, Peter Chi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/ecb6eb4b3da245efbbff43e501310a5d
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