Skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts

Abstract This study aimed to investigate antioxidant, anti-aging, and irritation properties of Thai edible insect extracts, including Bombyx mori, Omphisa fuscidentalis, Euconocephalus sp., Patanga succincta, Acheta domesticus, and Lethocerus indicus. Insects were extracted by 2 different methods, i...

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Autores principales:	Kankanit Yeerong, Suwannee Sriyab, Suvimol Somwongin, Chanun Punyoyai, Panuwan Chantawannakul, Songyot Anuchapreeda, Adchara Prommaban, Wantida Chaiyana
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ecb960a6683e4dc7a6bcb6db5e5822f7
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spelling	oai:doaj.org-article:ecb960a6683e4dc7a6bcb6db5e5822f72021-11-28T12:17:51ZSkin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts10.1038/s41598-021-02382-02045-2322https://doaj.org/article/ecb960a6683e4dc7a6bcb6db5e5822f72021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02382-0https://doaj.org/toc/2045-2322Abstract This study aimed to investigate antioxidant, anti-aging, and irritation properties of Thai edible insect extracts, including Bombyx mori, Omphisa fuscidentalis, Euconocephalus sp., Patanga succincta, Acheta domesticus, and Lethocerus indicus. Insects were extracted by 2 different methods, including maceration using ethanol or hexane and digestion using DI water. Then the extracts were determined for protein content using bicinchoninic acid assay and antioxidant activities using 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid), 2,2-diphenyl-1-picrylhydrazyl, ferric reducing antioxidant power, and ferric thiocyanate assays. Anti-aging activities were investigated by determination of collagenase and elastase inhibitory activities using spectrophotometric assay. Maceration by hexane yielded the highest extract content, whereas aqueous extract from digestion possessed the significantly highest protein content and biological activities (p < 0.05). Interestingly, aqueous extracts of A. domesticus possessed the significantly highest biological activities (p < 0.05) with Trolox equivalent antioxidant capacity value of 8.8 ± 0.1 mmol Trolox/mg, DPPH· inhibition of 19.5 ± 3.8%, equivalent concentration of 12.1 ± 0.7 µM FeSO4/mg, lipid peroxidation inhibition of 31.3 ± 2.4%, collagenase inhibition of 60.8 ± 2.1%, elastase inhibition of 17.0 ± 0.1%, and no irritation effect on chorioallantoic membrane and volunteers. Therefore, aqueous extract of A. domesticus would be suggested for further topical product development.Kankanit YeerongSuwannee SriyabSuvimol SomwonginChanun PunyoyaiPanuwan ChantawannakulSongyot AnuchapreedaAdchara PrommabanWantida ChaiyanaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kankanit Yeerong Suwannee Sriyab Suvimol Somwongin Chanun Punyoyai Panuwan Chantawannakul Songyot Anuchapreeda Adchara Prommaban Wantida Chaiyana Skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts
description	Abstract This study aimed to investigate antioxidant, anti-aging, and irritation properties of Thai edible insect extracts, including Bombyx mori, Omphisa fuscidentalis, Euconocephalus sp., Patanga succincta, Acheta domesticus, and Lethocerus indicus. Insects were extracted by 2 different methods, including maceration using ethanol or hexane and digestion using DI water. Then the extracts were determined for protein content using bicinchoninic acid assay and antioxidant activities using 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid), 2,2-diphenyl-1-picrylhydrazyl, ferric reducing antioxidant power, and ferric thiocyanate assays. Anti-aging activities were investigated by determination of collagenase and elastase inhibitory activities using spectrophotometric assay. Maceration by hexane yielded the highest extract content, whereas aqueous extract from digestion possessed the significantly highest protein content and biological activities (p < 0.05). Interestingly, aqueous extracts of A. domesticus possessed the significantly highest biological activities (p < 0.05) with Trolox equivalent antioxidant capacity value of 8.8 ± 0.1 mmol Trolox/mg, DPPH· inhibition of 19.5 ± 3.8%, equivalent concentration of 12.1 ± 0.7 µM FeSO4/mg, lipid peroxidation inhibition of 31.3 ± 2.4%, collagenase inhibition of 60.8 ± 2.1%, elastase inhibition of 17.0 ± 0.1%, and no irritation effect on chorioallantoic membrane and volunteers. Therefore, aqueous extract of A. domesticus would be suggested for further topical product development.
format	article
author	Kankanit Yeerong Suwannee Sriyab Suvimol Somwongin Chanun Punyoyai Panuwan Chantawannakul Songyot Anuchapreeda Adchara Prommaban Wantida Chaiyana
author_facet	Kankanit Yeerong Suwannee Sriyab Suvimol Somwongin Chanun Punyoyai Panuwan Chantawannakul Songyot Anuchapreeda Adchara Prommaban Wantida Chaiyana
author_sort	Kankanit Yeerong
title	Skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts
title_short	Skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts
title_full	Skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts
title_fullStr	Skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts
title_full_unstemmed	Skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts
title_sort	skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ecb960a6683e4dc7a6bcb6db5e5822f7
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Skin irritation and potential antioxidant, anti-collagenase, and anti-elastase activities of edible insect extracts

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