A nanodrug system overexpressed circRNA_0001805 alleviates nonalcoholic fatty liver disease via miR-106a-5p/miR-320a and ABCA1/CPT1 axis

Abstract Our study aimed to explore the function of circRNA_0001805 in the pathogenesis of NAFLD and the underlying mechanism. A nanodrug system (GA-RM/GZ/PL) was constructed to overexpress circRNA_0001805 specifically in hepatocytes for the treatment of NAFLD. Fat droplet accumulation in cultured c...

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Autores principales: Jian Li, Jing Qi, Yishu Tang, Huaizheng Liu, Kefu Zhou, Zheren Dai, Lehong Yuan, Chuanzheng Sun
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/ecbfc5068be34d87a8baff79d45d3bb4
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