Albumin in patients with liver disease shows an altered conformation

Paar et al. propose a SAXS-based approach to study conformations of human serum albumin (HSA) from patients with liver disease and a structural understanding of HSA dynamicity and its correlation with clinical variables are provided. Using it on real clinical samples, this study has concrete practic...

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Autores principales: Margret Paar, Vera H. Fengler, Daniel J. Rosenberg, Angelika Krebs, Rudolf E. Stauber, Karl Oettl, Michal Hammel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ecc3b7c9079f4242930538ca6ba2e0ab
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Sumario:Paar et al. propose a SAXS-based approach to study conformations of human serum albumin (HSA) from patients with liver disease and a structural understanding of HSA dynamicity and its correlation with clinical variables are provided. Using it on real clinical samples, this study has concrete practical implications too.