Albumin in patients with liver disease shows an altered conformation

Paar et al. propose a SAXS-based approach to study conformations of human serum albumin (HSA) from patients with liver disease and a structural understanding of HSA dynamicity and its correlation with clinical variables are provided. Using it on real clinical samples, this study has concrete practic...

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Autores principales: Margret Paar, Vera H. Fengler, Daniel J. Rosenberg, Angelika Krebs, Rudolf E. Stauber, Karl Oettl, Michal Hammel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/ecc3b7c9079f4242930538ca6ba2e0ab
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spelling oai:doaj.org-article:ecc3b7c9079f4242930538ca6ba2e0ab2021-12-02T16:04:13ZAlbumin in patients with liver disease shows an altered conformation10.1038/s42003-021-02269-w2399-3642https://doaj.org/article/ecc3b7c9079f4242930538ca6ba2e0ab2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02269-whttps://doaj.org/toc/2399-3642Paar et al. propose a SAXS-based approach to study conformations of human serum albumin (HSA) from patients with liver disease and a structural understanding of HSA dynamicity and its correlation with clinical variables are provided. Using it on real clinical samples, this study has concrete practical implications too.Margret PaarVera H. FenglerDaniel J. RosenbergAngelika KrebsRudolf E. StauberKarl OettlMichal HammelNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Margret Paar
Vera H. Fengler
Daniel J. Rosenberg
Angelika Krebs
Rudolf E. Stauber
Karl Oettl
Michal Hammel
Albumin in patients with liver disease shows an altered conformation
description Paar et al. propose a SAXS-based approach to study conformations of human serum albumin (HSA) from patients with liver disease and a structural understanding of HSA dynamicity and its correlation with clinical variables are provided. Using it on real clinical samples, this study has concrete practical implications too.
format article
author Margret Paar
Vera H. Fengler
Daniel J. Rosenberg
Angelika Krebs
Rudolf E. Stauber
Karl Oettl
Michal Hammel
author_facet Margret Paar
Vera H. Fengler
Daniel J. Rosenberg
Angelika Krebs
Rudolf E. Stauber
Karl Oettl
Michal Hammel
author_sort Margret Paar
title Albumin in patients with liver disease shows an altered conformation
title_short Albumin in patients with liver disease shows an altered conformation
title_full Albumin in patients with liver disease shows an altered conformation
title_fullStr Albumin in patients with liver disease shows an altered conformation
title_full_unstemmed Albumin in patients with liver disease shows an altered conformation
title_sort albumin in patients with liver disease shows an altered conformation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/ecc3b7c9079f4242930538ca6ba2e0ab
work_keys_str_mv AT margretpaar albumininpatientswithliverdiseaseshowsanalteredconformation
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AT angelikakrebs albumininpatientswithliverdiseaseshowsanalteredconformation
AT rudolfestauber albumininpatientswithliverdiseaseshowsanalteredconformation
AT karloettl albumininpatientswithliverdiseaseshowsanalteredconformation
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