A short discourse on vascular tissue engineering

Abstract Vascular tissue engineering has significant potential to make a major impact on a wide array of clinical problems. Continued progress in understanding basic vascular biology will be invaluable in making further advancements. Past and current achievements in tissue engineering of microvascul...

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Autores principales:	William G. Chang, Laura E. Niklason
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/ecc4208318c24c809359672ba18774b5
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spelling	oai:doaj.org-article:ecc4208318c24c809359672ba18774b52021-12-02T16:05:45ZA short discourse on vascular tissue engineering10.1038/s41536-017-0011-62057-3995https://doaj.org/article/ecc4208318c24c809359672ba18774b52017-03-01T00:00:00Zhttps://doi.org/10.1038/s41536-017-0011-6https://doaj.org/toc/2057-3995Abstract Vascular tissue engineering has significant potential to make a major impact on a wide array of clinical problems. Continued progress in understanding basic vascular biology will be invaluable in making further advancements. Past and current achievements in tissue engineering of microvasculature to perfuse organ specific constructs, small vessels for dialysis grafts, and modified synthetic and pediatric large caliber-vessel grafts will be discussed. An emphasis will be placed on clinical trial results with small and large-caliber vessel grafts. Challenges to achieving engineered constructs that satisfy the physiologic, immunologic, and manufacturing demands of engineered vasculature will be explored.William G. ChangLaura E. NiklasonNature PortfolioarticleMedicineRENnpj Regenerative Medicine, Vol 2, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R William G. Chang Laura E. Niklason A short discourse on vascular tissue engineering
description	Abstract Vascular tissue engineering has significant potential to make a major impact on a wide array of clinical problems. Continued progress in understanding basic vascular biology will be invaluable in making further advancements. Past and current achievements in tissue engineering of microvasculature to perfuse organ specific constructs, small vessels for dialysis grafts, and modified synthetic and pediatric large caliber-vessel grafts will be discussed. An emphasis will be placed on clinical trial results with small and large-caliber vessel grafts. Challenges to achieving engineered constructs that satisfy the physiologic, immunologic, and manufacturing demands of engineered vasculature will be explored.
format	article
author	William G. Chang Laura E. Niklason
author_facet	William G. Chang Laura E. Niklason
author_sort	William G. Chang
title	A short discourse on vascular tissue engineering
title_short	A short discourse on vascular tissue engineering
title_full	A short discourse on vascular tissue engineering
title_fullStr	A short discourse on vascular tissue engineering
title_full_unstemmed	A short discourse on vascular tissue engineering
title_sort	short discourse on vascular tissue engineering
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ecc4208318c24c809359672ba18774b5
work_keys_str_mv	AT williamgchang ashortdiscourseonvasculartissueengineering AT lauraeniklason ashortdiscourseonvasculartissueengineering AT williamgchang shortdiscourseonvasculartissueengineering AT lauraeniklason shortdiscourseonvasculartissueengineering
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A short discourse on vascular tissue engineering

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