Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice

Broadly reactive antibodies that recognize influenza A virus HA can be protective, but the mechanism is not completely understood. Here, He et al. show that the inflammatory response and phagocytosis mediated by the interaction between protective antibodies and macrophages are essential for protecti...

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Autores principales: Wenqian He, Chi-Jene Chen, Caitlin E. Mullarkey, Jennifer R. Hamilton, Christine K. Wong, Paul E. Leon, Melissa B. Uccellini, Veronika Chromikova, Carole Henry, Kevin W. Hoffman, Jean K. Lim, Patrick C. Wilson, Matthew S. Miller, Florian Krammer, Peter Palese, Gene S. Tan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Science
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Acceso en línea:https://doaj.org/article/ecc73d871ca24888b8f3af7ce766d50b
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