Multivalent nanoparticle-based vaccines protect hamsters against SARS-CoV-2 after a single immunization

Chiba et al. describe the use of MS2 bacteriophage coat proteins to develop nanocarriers that display the SARS-CoV-2 spike proteins multivalently for vaccine applications. The vaccine elicited high neutralizing antibody titers and protected Syrian hamsters from virus infection after a single immuniz...

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Bibliographic Details
Main Authors: Shiho Chiba, Steven J. Frey, Peter J. Halfmann, Makoto Kuroda, Tadashi Maemura, Jie E. Yang, Elizabeth R. Wright, Yoshihiro Kawaoka, Ravi S. Kane
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/eccc0e36630d4307b1d6da12b00abf09
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