Construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data

Abstract Background We aimed to build a common terminology in the domain of cervical cancer, named Cervical Cancer Common Terminology (CCCT), that will facilitate clinical data exchange, ensure quality of data and support large scale data analysis. Methods The standard concepts and relations of CCCT...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Na Hong, Fengxiang Chang, Zhengjie Ou, Yishang Wang, Yating Yang, Qiang Guo, Jianhui Ma, Dan Zhao
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Cervical cancer Common terminology Interoperability Clinical terms Electronic health records Computer applications to medicine. Medical informatics R858-859.7
Acceso en línea:	https://doaj.org/article/eccc519bac414f8ca4dd40a4abeba4ca
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:eccc519bac414f8ca4dd40a4abeba4ca
record_format	dspace
spelling	oai:doaj.org-article:eccc519bac414f8ca4dd40a4abeba4ca2021-11-21T12:28:55ZConstruction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data10.1186/s12911-021-01672-x1472-6947https://doaj.org/article/eccc519bac414f8ca4dd40a4abeba4ca2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12911-021-01672-xhttps://doaj.org/toc/1472-6947Abstract Background We aimed to build a common terminology in the domain of cervical cancer, named Cervical Cancer Common Terminology (CCCT), that will facilitate clinical data exchange, ensure quality of data and support large scale data analysis. Methods The standard concepts and relations of CCCT were collected from ICD-10-CM Chinese Version, ICD-9-PC Chinese Version, officially issued commonly used Chinese clinical terms, Chinese guidelines for diagnosis and treatment of cervical cancer and Chinese medical book Lin Qiaozhi Gynecologic Oncology. 2062 cervical cancer electronic medical records (EMRs) from 16 hospitals, belong to different regions and hospital tiers, were collected for terminology enrichment and building common terms and relations. Concepts hierarchies, terms and relationships were built using Protégé. The performance of natural language processing results was evaluated by average precision, recall, and F1-score. The usability of CCCT were evaluated by terminology coverage. Results A total of 880 standard concepts, 1182 common terms, 16 relations and 6 attributes were defined in CCCT, which organized in 6 levels and 11 classes. Initial evaluation of the natural language processing results demonstrated average precision, recall, and F1-score percentages of 96%, 72.6%, and 88.5%. The average terminology coverage for three classes of terms, clinical manifestation, treatment, and pathology, were 87.22%, 92.63%, and 89.85%, respectively. Flexible Chinese expressions exist between regions, traditions, cultures, and language habits within the country, linguistic variations in different settings and diverse translation of introduced western language terms are the main reasons of uncovered terms. Conclusions Our study demonstrated the initial results of CCCT construction. This study is an ongoing work, with the update of medical knowledge, more standard clinical concepts will be added in, and with more EMRs to be collected and analyzed, the term coverage will be continuing improved. In the future, CCCT will effectively support clinical data analysis in large scale.Na HongFengxiang ChangZhengjie OuYishang WangYating YangQiang GuoJianhui MaDan ZhaoBMCarticleCervical cancerCommon terminologyInteroperabilityClinical termsElectronic health recordsComputer applications to medicine. Medical informaticsR858-859.7ENBMC Medical Informatics and Decision Making, Vol 21, Iss S9, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cervical cancer Common terminology Interoperability Clinical terms Electronic health records Computer applications to medicine. Medical informatics R858-859.7
spellingShingle	Cervical cancer Common terminology Interoperability Clinical terms Electronic health records Computer applications to medicine. Medical informatics R858-859.7 Na Hong Fengxiang Chang Zhengjie Ou Yishang Wang Yating Yang Qiang Guo Jianhui Ma Dan Zhao Construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data
description	Abstract Background We aimed to build a common terminology in the domain of cervical cancer, named Cervical Cancer Common Terminology (CCCT), that will facilitate clinical data exchange, ensure quality of data and support large scale data analysis. Methods The standard concepts and relations of CCCT were collected from ICD-10-CM Chinese Version, ICD-9-PC Chinese Version, officially issued commonly used Chinese clinical terms, Chinese guidelines for diagnosis and treatment of cervical cancer and Chinese medical book Lin Qiaozhi Gynecologic Oncology. 2062 cervical cancer electronic medical records (EMRs) from 16 hospitals, belong to different regions and hospital tiers, were collected for terminology enrichment and building common terms and relations. Concepts hierarchies, terms and relationships were built using Protégé. The performance of natural language processing results was evaluated by average precision, recall, and F1-score. The usability of CCCT were evaluated by terminology coverage. Results A total of 880 standard concepts, 1182 common terms, 16 relations and 6 attributes were defined in CCCT, which organized in 6 levels and 11 classes. Initial evaluation of the natural language processing results demonstrated average precision, recall, and F1-score percentages of 96%, 72.6%, and 88.5%. The average terminology coverage for three classes of terms, clinical manifestation, treatment, and pathology, were 87.22%, 92.63%, and 89.85%, respectively. Flexible Chinese expressions exist between regions, traditions, cultures, and language habits within the country, linguistic variations in different settings and diverse translation of introduced western language terms are the main reasons of uncovered terms. Conclusions Our study demonstrated the initial results of CCCT construction. This study is an ongoing work, with the update of medical knowledge, more standard clinical concepts will be added in, and with more EMRs to be collected and analyzed, the term coverage will be continuing improved. In the future, CCCT will effectively support clinical data analysis in large scale.
format	article
author	Na Hong Fengxiang Chang Zhengjie Ou Yishang Wang Yating Yang Qiang Guo Jianhui Ma Dan Zhao
author_facet	Na Hong Fengxiang Chang Zhengjie Ou Yishang Wang Yating Yang Qiang Guo Jianhui Ma Dan Zhao
author_sort	Na Hong
title	Construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data
title_short	Construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data
title_full	Construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data
title_fullStr	Construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data
title_full_unstemmed	Construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data
title_sort	construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of chinese clinical data
publisher	BMC
publishDate	2021
url	https://doaj.org/article/eccc519bac414f8ca4dd40a4abeba4ca
work_keys_str_mv	AT nahong constructionofthecervicalcancercommonterminologyforpromotingsemanticinteroperabilityandutilizationofchineseclinicaldata AT fengxiangchang constructionofthecervicalcancercommonterminologyforpromotingsemanticinteroperabilityandutilizationofchineseclinicaldata AT zhengjieou constructionofthecervicalcancercommonterminologyforpromotingsemanticinteroperabilityandutilizationofchineseclinicaldata AT yishangwang constructionofthecervicalcancercommonterminologyforpromotingsemanticinteroperabilityandutilizationofchineseclinicaldata AT yatingyang constructionofthecervicalcancercommonterminologyforpromotingsemanticinteroperabilityandutilizationofchineseclinicaldata AT qiangguo constructionofthecervicalcancercommonterminologyforpromotingsemanticinteroperabilityandutilizationofchineseclinicaldata AT jianhuima constructionofthecervicalcancercommonterminologyforpromotingsemanticinteroperabilityandutilizationofchineseclinicaldata AT danzhao constructionofthecervicalcancercommonterminologyforpromotingsemanticinteroperabilityandutilizationofchineseclinicaldata
_version_	1718419039251857408

Construction of the cervical cancer common terminology for promoting semantic interoperability and utilization of Chinese clinical data

Ejemplares similares