Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response

The vascularization of the testis through testicular artery is of great importance to maintain its normal function. The vascular disruption due to inadequate arterial blood flow of the testis negatively affects testicular function and semen quality. This study aimed to determine the efficacy of g...

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Autores principales:	Mohammed Rawy, Gaber Megahed, Abdelbaset Eweda Abdelbaset, Ahmed Saad Ahmed Hassaneen
Formato:	article
Lenguaje:	EN
Publicado:	South Valley University 2021
Materias:	fertility gnrh testicular artery testicular blood flow testosterone Agriculture S Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/eccdd48b650c48a2a939b5bea681d049
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spelling	oai:doaj.org-article:eccdd48b650c48a2a939b5bea681d0492021-12-02T17:46:32ZEvaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response10.21608/svu.2021.70099.11172535-18262535-1877https://doaj.org/article/eccdd48b650c48a2a939b5bea681d0492021-06-01T00:00:00Zhttps://svu.journals.ekb.eg/article_177650.htmlhttps://doaj.org/toc/2535-1826https://doaj.org/toc/2535-1877The vascularization of the testis through testicular artery is of great importance to maintain its normal function. The vascular disruption due to inadequate arterial blood flow of the testis negatively affects testicular function and semen quality. This study aimed to determine the efficacy of gonadotropin-releasing hormone (GnRH) administration on testicular vascularity in relation to testosterone hormonal response. Five clinically healthy adult ossimi rams 18- to 30-months-old were used. Testicular arteries Doppler examination, blood sampling following GnRH administration and testosterone hormonal assay were conducted. Both pulsatility index (PI) and resistance index (RI) significantly decreased in all treated rams starting from 1 hr till 120 hrs after single GnRH administration, both Doppler indices returned to their pre-treatment values at 144 hours after GnRH administration. Doppler peak systolic velocity (PSV) did not change in response to GnRH administration. Testosterone hormone concentrations negatively correlated with PI and RI but not PSV. In conclusion, GnRH would be useful a beneficial therapy for the treatment of testicular dysfunction in rams by increasing testosterone concentrations and testicular blood flow. And pulse wave Doppler ultrasonography would be a useful non-invasive clinical tool for evaluation of the efficacy of novel therapeutic treatments in ramsMohammed RawyGaber Megahed Abdelbaset Eweda AbdelbasetAhmed Saad Ahmed HassaneenSouth Valley Universityarticlefertilitygnrhtesticular arterytesticular blood flowtestosteroneAgricultureSVeterinary medicineSF600-1100ENSVU-International Journal of Veterinary Sciences, Vol 4, Iss 2, Pp 60-75 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	fertility gnrh testicular artery testicular blood flow testosterone Agriculture S Veterinary medicine SF600-1100
spellingShingle	fertility gnrh testicular artery testicular blood flow testosterone Agriculture S Veterinary medicine SF600-1100 Mohammed Rawy Gaber Megahed Abdelbaset Eweda Abdelbaset Ahmed Saad Ahmed Hassaneen Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response
description	The vascularization of the testis through testicular artery is of great importance to maintain its normal function. The vascular disruption due to inadequate arterial blood flow of the testis negatively affects testicular function and semen quality. This study aimed to determine the efficacy of gonadotropin-releasing hormone (GnRH) administration on testicular vascularity in relation to testosterone hormonal response. Five clinically healthy adult ossimi rams 18- to 30-months-old were used. Testicular arteries Doppler examination, blood sampling following GnRH administration and testosterone hormonal assay were conducted. Both pulsatility index (PI) and resistance index (RI) significantly decreased in all treated rams starting from 1 hr till 120 hrs after single GnRH administration, both Doppler indices returned to their pre-treatment values at 144 hours after GnRH administration. Doppler peak systolic velocity (PSV) did not change in response to GnRH administration. Testosterone hormone concentrations negatively correlated with PI and RI but not PSV. In conclusion, GnRH would be useful a beneficial therapy for the treatment of testicular dysfunction in rams by increasing testosterone concentrations and testicular blood flow. And pulse wave Doppler ultrasonography would be a useful non-invasive clinical tool for evaluation of the efficacy of novel therapeutic treatments in rams
format	article
author	Mohammed Rawy Gaber Megahed Abdelbaset Eweda Abdelbaset Ahmed Saad Ahmed Hassaneen
author_facet	Mohammed Rawy Gaber Megahed Abdelbaset Eweda Abdelbaset Ahmed Saad Ahmed Hassaneen
author_sort	Mohammed Rawy
title	Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response
title_short	Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response
title_full	Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response
title_fullStr	Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response
title_full_unstemmed	Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response
title_sort	evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave doppler in rams and their relation to hormonal response
publisher	South Valley University
publishDate	2021
url	https://doaj.org/article/eccdd48b650c48a2a939b5bea681d049
work_keys_str_mv	AT mohammedrawy evaluationoftesticularhemodynamicsfollowinggonadotropinreleasinghormoneadministrationwiththeaidofpulsewavedopplerinramsandtheirrelationtohormonalresponse AT gabermegahed evaluationoftesticularhemodynamicsfollowinggonadotropinreleasinghormoneadministrationwiththeaidofpulsewavedopplerinramsandtheirrelationtohormonalresponse AT abdelbasetewedaabdelbaset evaluationoftesticularhemodynamicsfollowinggonadotropinreleasinghormoneadministrationwiththeaidofpulsewavedopplerinramsandtheirrelationtohormonalresponse AT ahmedsaadahmedhassaneen evaluationoftesticularhemodynamicsfollowinggonadotropinreleasinghormoneadministrationwiththeaidofpulsewavedopplerinramsandtheirrelationtohormonalresponse
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Evaluation of testicular hemodynamics following gonadotropin-releasing hormone administration with the aid of pulse wave Doppler in rams and their relation to hormonal response

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