The structure of iPLA2β reveals dimeric active sites and suggests mechanisms of regulation and localization

The structure of iPLA2β reveals dimeric active sites and suggests mechanisms of regulation and localization

Calcium-independent phospholipase A2β (iPLA2β) is involved in many physiological and pathological processes but the underlying mechanisms are largely unknown. Here, the authors present the structure of dimeric iPLA2β, providing insights into the regulation of its activity and cellular localization....

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Autores principales: Konstantin R. Malley, Olga Koroleva, Ian Miller, Ruslan Sanishvili, Christopher M. Jenkins, Richard W. Gross, Sergey Korolev
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/eccf36650d4148448f5ea5a4adc113d8
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