SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS

We have analyzed the results of combined clinical laboratory study in 100 patients, in whom abdominal sepsis was diagnosed. Along with a standard protocol of medical and diagnostic measures, all the patients underwent immunological examination, i.e., populations and subpopulations of immunocompetent...

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Autores principales:	V. V. Grebenuyk, N. V. Yusan
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	abdominal sepsis sepsis prediction lymphocytes immune regulation index il-1ra Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/eccf75df63bd4fc886856e8d71af4ea3
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id	oai:doaj.org-article:eccf75df63bd4fc886856e8d71af4ea3
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spelling	oai:doaj.org-article:eccf75df63bd4fc886856e8d71af4ea32021-11-18T08:03:38ZSIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS1563-06252313-741X10.15789/1563-0625-2010-3-253-258https://doaj.org/article/eccf75df63bd4fc886856e8d71af4ea32014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/102https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XWe have analyzed the results of combined clinical laboratory study in 100 patients, in whom abdominal sepsis was diagnosed. Along with a standard protocol of medical and diagnostic measures, all the patients underwent immunological examination, i.e., populations and subpopulations of immunocompetent cells were defined by indirect immunofluorescence method, immunoglobulins of main types, and serum cytokines were defined by means of immune-enzyme assay. Immunoregulatory index and levels of IL-1ra in blood serum significantly correlated with severe state and disease outcomes in the patients with abdominal sepsis. Due to such characteristic features, the CD4+/CD8+ ratio and IL-1ra level were are included into a proposed list of parameters able to predict fatal outcome in the patients with abdominal sepsis.V. V. GrebenuykN. V. YusanSPb RAACIarticleabdominal sepsissepsis predictionlymphocytesimmune regulation indexil-1raImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 3, Pp 253-258 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	abdominal sepsis sepsis prediction lymphocytes immune regulation index il-1ra Immunologic diseases. Allergy RC581-607
spellingShingle	abdominal sepsis sepsis prediction lymphocytes immune regulation index il-1ra Immunologic diseases. Allergy RC581-607 V. V. Grebenuyk N. V. Yusan SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS
description	We have analyzed the results of combined clinical laboratory study in 100 patients, in whom abdominal sepsis was diagnosed. Along with a standard protocol of medical and diagnostic measures, all the patients underwent immunological examination, i.e., populations and subpopulations of immunocompetent cells were defined by indirect immunofluorescence method, immunoglobulins of main types, and serum cytokines were defined by means of immune-enzyme assay. Immunoregulatory index and levels of IL-1ra in blood serum significantly correlated with severe state and disease outcomes in the patients with abdominal sepsis. Due to such characteristic features, the CD4+/CD8+ ratio and IL-1ra level were are included into a proposed list of parameters able to predict fatal outcome in the patients with abdominal sepsis.
format	article
author	V. V. Grebenuyk N. V. Yusan
author_facet	V. V. Grebenuyk N. V. Yusan
author_sort	V. V. Grebenuyk
title	SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS
title_short	SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS
title_full	SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS
title_fullStr	SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS
title_full_unstemmed	SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS
title_sort	significance of immune indexes in severity evaluation in the patients with abdominal sepsis
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/eccf75df63bd4fc886856e8d71af4ea3
work_keys_str_mv	AT vvgrebenuyk significanceofimmuneindexesinseverityevaluationinthepatientswithabdominalsepsis AT nvyusan significanceofimmuneindexesinseverityevaluationinthepatientswithabdominalsepsis
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SIGNIFICANCE OF IMMUNE INDEXES IN SEVERITY EVALUATION IN THE PATIENTS WITH ABDOMINAL SEPSIS

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