Cytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells

Different therapeutic approaches, comprising surgery, radiotherapy, chemotherapy are used for cancer treatment. There is an extreme need for novel anti-cancer agents with minimal toxicity for normal cells that are significantly growing. Nowadays, bacteriocins or antimicrobial peptides (AMPs) are co...

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Autores principales:	Samira Karimaei, Leonardo Oliveira Reis
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2020
Materias:	cancer nisin cancer cells chemotherapy Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/ecd430b6e6fe44ec9d55ff4c60f119f4
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spelling	oai:doaj.org-article:ecd430b6e6fe44ec9d55ff4c60f119f42021-11-28T09:58:59ZCytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells10.22034/TRU.2020.255094.10382717-042Xhttps://doaj.org/article/ecd430b6e6fe44ec9d55ff4c60f119f42020-05-01T00:00:00Zhttps://www.transresurology.com/article_118875.htmlhttps://doaj.org/toc/2717-042XDifferent therapeutic approaches, comprising surgery, radiotherapy, chemotherapy are used for cancer treatment. There is an extreme need for novel anti-cancer agents with minimal toxicity for normal cells that are significantly growing. Nowadays, bacteriocins or antimicrobial peptides (AMPs) are considered tumor cell killers. In this regard, Nisin is one of the natural AMPs produced by Lactococcus lactis. Considering that Nisin could make apoptosis through inherent pathways and cause cancer cell death, it was suggested that at appropriate doses it might be efficient and safe for cancer treatment, room for future studies.Samira Karimaei Leonardo Oliveira ReisUrology Research Centerarticlecancernisincancer cellschemotherapyDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 2, Iss 2, Pp 45-47 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	cancer nisin cancer cells chemotherapy Diseases of the genitourinary system. Urology RC870-923
spellingShingle	cancer nisin cancer cells chemotherapy Diseases of the genitourinary system. Urology RC870-923 Samira Karimaei Leonardo Oliveira Reis Cytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells
description	Different therapeutic approaches, comprising surgery, radiotherapy, chemotherapy are used for cancer treatment. There is an extreme need for novel anti-cancer agents with minimal toxicity for normal cells that are significantly growing. Nowadays, bacteriocins or antimicrobial peptides (AMPs) are considered tumor cell killers. In this regard, Nisin is one of the natural AMPs produced by Lactococcus lactis. Considering that Nisin could make apoptosis through inherent pathways and cause cancer cell death, it was suggested that at appropriate doses it might be efficient and safe for cancer treatment, room for future studies.
format	article
author	Samira Karimaei Leonardo Oliveira Reis
author_facet	Samira Karimaei Leonardo Oliveira Reis
author_sort	Samira Karimaei
title	Cytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells
title_short	Cytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells
title_full	Cytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells
title_fullStr	Cytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells
title_full_unstemmed	Cytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells
title_sort	cytotoxicity and apoptotic effect of nisin as an effective bacteriocin on the cancer cells
publisher	Urology Research Center
publishDate	2020
url	https://doaj.org/article/ecd430b6e6fe44ec9d55ff4c60f119f4
work_keys_str_mv	AT samirakarimaei cytotoxicityandapoptoticeffectofnisinasaneffectivebacteriocinonthecancercells AT leonardooliveirareis cytotoxicityandapoptoticeffectofnisinasaneffectivebacteriocinonthecancercells
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Cytotoxicity and Apoptotic Effect of Nisin as an Effective Bacteriocin on the Cancer Cells

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