Preparing for genomic medicine: a real world demonstration of health system change

Abstract Organisations and governments seeking to implement genomics into clinical practice face numerous challenges across multiple, diverse aspects of the health care system. It is not sufficient to tackle any one aspect in isolation: to create a system that supports genomic medicine, they must be...

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Autores principales:	Clara L. Gaff, Ingrid M. Winship, Susan M. Forrest, David P. Hansen, Julian Clark, Paul M. Waring, Mike South, Andrew H. Sinclair
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Genetics QH426-470
Acceso en línea:	https://doaj.org/article/ecdf879dcb8d45b98118434e30c38fcc
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spelling	oai:doaj.org-article:ecdf879dcb8d45b98118434e30c38fcc2021-12-02T12:34:18ZPreparing for genomic medicine: a real world demonstration of health system change10.1038/s41525-017-0017-42056-7944https://doaj.org/article/ecdf879dcb8d45b98118434e30c38fcc2017-05-01T00:00:00Zhttps://doi.org/10.1038/s41525-017-0017-4https://doaj.org/toc/2056-7944Abstract Organisations and governments seeking to implement genomics into clinical practice face numerous challenges across multiple, diverse aspects of the health care system. It is not sufficient to tackle any one aspect in isolation: to create a system that supports genomic medicine, they must be addressed simultaneously. The growing body of global knowledge can guide decision-making, but each jurisdiction or organisation needs a model for genomic (or personalised) medicine that is tailored to its unique context, its priorities and the funds available. Poor decisions could greatly reduce the benefits that could potentially arise from genomic medicine. Demonstration projects enable models to be tested, providing valuable evidence and experience for subsequent implementation. Here, we present the Melbourne Genomics Health Alliance demonstration project as an exemplar of a collaborative, holistic approach to phased implementation of genomics across multiple autonomous institutions. The approach and lessons learned may assist others in determining how best to integrate genomics into their healthcare system.Clara L. GaffIngrid M. WinshipSusan M. ForrestDavid P. HansenJulian ClarkPaul M. WaringMike SouthAndrew H. SinclairNature PortfolioarticleMedicineRGeneticsQH426-470ENnpj Genomic Medicine, Vol 2, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Genetics QH426-470
spellingShingle	Medicine R Genetics QH426-470 Clara L. Gaff Ingrid M. Winship Susan M. Forrest David P. Hansen Julian Clark Paul M. Waring Mike South Andrew H. Sinclair Preparing for genomic medicine: a real world demonstration of health system change
description	Abstract Organisations and governments seeking to implement genomics into clinical practice face numerous challenges across multiple, diverse aspects of the health care system. It is not sufficient to tackle any one aspect in isolation: to create a system that supports genomic medicine, they must be addressed simultaneously. The growing body of global knowledge can guide decision-making, but each jurisdiction or organisation needs a model for genomic (or personalised) medicine that is tailored to its unique context, its priorities and the funds available. Poor decisions could greatly reduce the benefits that could potentially arise from genomic medicine. Demonstration projects enable models to be tested, providing valuable evidence and experience for subsequent implementation. Here, we present the Melbourne Genomics Health Alliance demonstration project as an exemplar of a collaborative, holistic approach to phased implementation of genomics across multiple autonomous institutions. The approach and lessons learned may assist others in determining how best to integrate genomics into their healthcare system.
format	article
author	Clara L. Gaff Ingrid M. Winship Susan M. Forrest David P. Hansen Julian Clark Paul M. Waring Mike South Andrew H. Sinclair
author_facet	Clara L. Gaff Ingrid M. Winship Susan M. Forrest David P. Hansen Julian Clark Paul M. Waring Mike South Andrew H. Sinclair
author_sort	Clara L. Gaff
title	Preparing for genomic medicine: a real world demonstration of health system change
title_short	Preparing for genomic medicine: a real world demonstration of health system change
title_full	Preparing for genomic medicine: a real world demonstration of health system change
title_fullStr	Preparing for genomic medicine: a real world demonstration of health system change
title_full_unstemmed	Preparing for genomic medicine: a real world demonstration of health system change
title_sort	preparing for genomic medicine: a real world demonstration of health system change
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ecdf879dcb8d45b98118434e30c38fcc
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Preparing for genomic medicine: a real world demonstration of health system change

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