Structural Evolution of TIR-Domain Signalosomes
TIR (Toll/interleukin-1 receptor/resistance protein) domains are cytoplasmic domains widely found in animals and plants, where they are essential components of the innate immune system. A key feature of TIR-domain function in signaling is weak and transient self-association and association with othe...
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Main Authors: | Surekha Nimma, Weixi Gu, Natsumi Maruta, Yan Li, Mengqi Pan, Forhad Karim Saikot, Bryan Y. J. Lim, Helen Ying McGuinness, Zannati Ferdous Zaoti, Sulin Li, Sneha Desa, Mohammad Kawsar Manik, Jeffrey D. Nanson, Bostjan Kobe |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Online Access: | https://doaj.org/article/ece1b08c56e44d039e4b4de42f74e856 |
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