Structural Evolution of TIR-Domain Signalosomes

TIR (Toll/interleukin-1 receptor/resistance protein) domains are cytoplasmic domains widely found in animals and plants, where they are essential components of the innate immune system. A key feature of TIR-domain function in signaling is weak and transient self-association and association with othe...

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Auteurs principaux:	Surekha Nimma, Weixi Gu, Natsumi Maruta, Yan Li, Mengqi Pan, Forhad Karim Saikot, Bryan Y. J. Lim, Helen Ying McGuinness, Zannati Ferdous Zaoti, Sulin Li, Sneha Desa, Mohammad Kawsar Manik, Jeffrey D. Nanson, Bostjan Kobe
Format:	article
Langue:	EN
Publié:	Frontiers Media S.A. 2021
Sujets:	protein structure protein-protein interactions axon degeneration cell-death signaling signaling by cooperative assembly formation (SCAF) innate immunity Immunologic diseases. Allergy RC581-607
Accès en ligne:	https://doaj.org/article/ece1b08c56e44d039e4b4de42f74e856
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Structural Evolution of TIR-Domain Signalosomes

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