Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury

The oligodendrocyte lineage is known for its transcriptional heterogeneity, but the functional consequences of this are unclear. Here, the authors show that distinct populations of mature oligodendrocytes have spatial preferences in the brain and spinal cord and show different responses to spinal co...

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Autores principales:	Elisa M. Floriddia, Tânia Lourenço, Shupei Zhang, David van Bruggen, Markus M. Hilscher, Petra Kukanja, João P. Gonçalves dos Santos, Müge Altınkök, Chika Yokota, Enric Llorens-Bobadilla, Sara B. Mulinyawe, Mário Grãos, Lu O. Sun, Jonas Frisén, Mats Nilsson, Gonçalo Castelo-Branco
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ece367487961471eb842a80b9dcd6fef
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spelling	oai:doaj.org-article:ece367487961471eb842a80b9dcd6fef2021-12-02T16:56:35ZDistinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury10.1038/s41467-020-19453-x2041-1723https://doaj.org/article/ece367487961471eb842a80b9dcd6fef2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19453-xhttps://doaj.org/toc/2041-1723The oligodendrocyte lineage is known for its transcriptional heterogeneity, but the functional consequences of this are unclear. Here, the authors show that distinct populations of mature oligodendrocytes have spatial preferences in the brain and spinal cord and show different responses to spinal cord injury.Elisa M. FloriddiaTânia LourençoShupei ZhangDavid van BruggenMarkus M. HilscherPetra KukanjaJoão P. Gonçalves dos SantosMüge AltınkökChika YokotaEnric Llorens-BobadillaSara B. MulinyaweMário GrãosLu O. SunJonas FrisénMats NilssonGonçalo Castelo-BrancoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elisa M. Floriddia Tânia Lourenço Shupei Zhang David van Bruggen Markus M. Hilscher Petra Kukanja João P. Gonçalves dos Santos Müge Altınkök Chika Yokota Enric Llorens-Bobadilla Sara B. Mulinyawe Mário Grãos Lu O. Sun Jonas Frisén Mats Nilsson Gonçalo Castelo-Branco Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
description	The oligodendrocyte lineage is known for its transcriptional heterogeneity, but the functional consequences of this are unclear. Here, the authors show that distinct populations of mature oligodendrocytes have spatial preferences in the brain and spinal cord and show different responses to spinal cord injury.
format	article
author	Elisa M. Floriddia Tânia Lourenço Shupei Zhang David van Bruggen Markus M. Hilscher Petra Kukanja João P. Gonçalves dos Santos Müge Altınkök Chika Yokota Enric Llorens-Bobadilla Sara B. Mulinyawe Mário Grãos Lu O. Sun Jonas Frisén Mats Nilsson Gonçalo Castelo-Branco
author_facet	Elisa M. Floriddia Tânia Lourenço Shupei Zhang David van Bruggen Markus M. Hilscher Petra Kukanja João P. Gonçalves dos Santos Müge Altınkök Chika Yokota Enric Llorens-Bobadilla Sara B. Mulinyawe Mário Grãos Lu O. Sun Jonas Frisén Mats Nilsson Gonçalo Castelo-Branco
author_sort	Elisa M. Floriddia
title	Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
title_short	Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
title_full	Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
title_fullStr	Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
title_full_unstemmed	Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
title_sort	distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ece367487961471eb842a80b9dcd6fef
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Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury

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