Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum

This genome-wide association study identifies five significant SNPs in two loci which are associated with the epigenetic age of post-mortem cerebellar tissue according to a DNA methylation based biomarker of human aging.

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Autores principales: Ake T. Lu, Eilis Hannon, Morgan E. Levine, Ke Hao, Eileen M. Crimmins, Katie Lunnon, Alexey Kozlenkov, Jonathan Mill, Stella Dracheva, Steve Horvath
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/ecf560846a064876b0a7695cf82508d6
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spelling oai:doaj.org-article:ecf560846a064876b0a7695cf82508d62021-12-02T16:57:05ZGenetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum10.1038/ncomms105612041-1723https://doaj.org/article/ecf560846a064876b0a7695cf82508d62016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10561https://doaj.org/toc/2041-1723This genome-wide association study identifies five significant SNPs in two loci which are associated with the epigenetic age of post-mortem cerebellar tissue according to a DNA methylation based biomarker of human aging.Ake T. LuEilis HannonMorgan E. LevineKe HaoEileen M. CrimminsKatie LunnonAlexey KozlenkovJonathan MillStella DrachevaSteve HorvathNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ake T. Lu
Eilis Hannon
Morgan E. Levine
Ke Hao
Eileen M. Crimmins
Katie Lunnon
Alexey Kozlenkov
Jonathan Mill
Stella Dracheva
Steve Horvath
Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum
description This genome-wide association study identifies five significant SNPs in two loci which are associated with the epigenetic age of post-mortem cerebellar tissue according to a DNA methylation based biomarker of human aging.
format article
author Ake T. Lu
Eilis Hannon
Morgan E. Levine
Ke Hao
Eileen M. Crimmins
Katie Lunnon
Alexey Kozlenkov
Jonathan Mill
Stella Dracheva
Steve Horvath
author_facet Ake T. Lu
Eilis Hannon
Morgan E. Levine
Ke Hao
Eileen M. Crimmins
Katie Lunnon
Alexey Kozlenkov
Jonathan Mill
Stella Dracheva
Steve Horvath
author_sort Ake T. Lu
title Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum
title_short Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum
title_full Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum
title_fullStr Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum
title_full_unstemmed Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum
title_sort genetic variants near mlst8 and dhx57 affect the epigenetic age of the cerebellum
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/ecf560846a064876b0a7695cf82508d6
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