Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation

Mechanoelectrical transducer (MET) channels on the tips of inner hair cells are essential for transducing auditory sensory information. Here, the authors show that disrupting MET channel function also prevents the preservation of normal inner hair cell identity in adult mice.

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Autores principales:	Laura F. Corns, Stuart L. Johnson, Terri Roberts, Kishani M. Ranatunga, Aenea Hendry, Federico Ceriani, Saaid Safieddine, Karen P. Steel, Andy Forge, Christine Petit, David N. Furness, Corné J. Kros, Walter Marcotti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ecfdf3bfbfef42019680748d1efaa1ea
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spelling	oai:doaj.org-article:ecfdf3bfbfef42019680748d1efaa1ea2021-12-02T15:34:25ZMechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation10.1038/s41467-018-06307-w2041-1723https://doaj.org/article/ecfdf3bfbfef42019680748d1efaa1ea2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06307-whttps://doaj.org/toc/2041-1723Mechanoelectrical transducer (MET) channels on the tips of inner hair cells are essential for transducing auditory sensory information. Here, the authors show that disrupting MET channel function also prevents the preservation of normal inner hair cell identity in adult mice.Laura F. CornsStuart L. JohnsonTerri RobertsKishani M. RanatungaAenea HendryFederico CerianiSaaid SafieddineKaren P. SteelAndy ForgeChristine PetitDavid N. FurnessCorné J. KrosWalter MarcottiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Laura F. Corns Stuart L. Johnson Terri Roberts Kishani M. Ranatunga Aenea Hendry Federico Ceriani Saaid Safieddine Karen P. Steel Andy Forge Christine Petit David N. Furness Corné J. Kros Walter Marcotti Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation
description	Mechanoelectrical transducer (MET) channels on the tips of inner hair cells are essential for transducing auditory sensory information. Here, the authors show that disrupting MET channel function also prevents the preservation of normal inner hair cell identity in adult mice.
format	article
author	Laura F. Corns Stuart L. Johnson Terri Roberts Kishani M. Ranatunga Aenea Hendry Federico Ceriani Saaid Safieddine Karen P. Steel Andy Forge Christine Petit David N. Furness Corné J. Kros Walter Marcotti
author_facet	Laura F. Corns Stuart L. Johnson Terri Roberts Kishani M. Ranatunga Aenea Hendry Federico Ceriani Saaid Safieddine Karen P. Steel Andy Forge Christine Petit David N. Furness Corné J. Kros Walter Marcotti
author_sort	Laura F. Corns
title	Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation
title_short	Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation
title_full	Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation
title_fullStr	Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation
title_full_unstemmed	Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation
title_sort	mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/ecfdf3bfbfef42019680748d1efaa1ea
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Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation

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