The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element

6-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a sign...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Agnieszka Markowska, Adam Roman Markowski, Iwona Jarocka-Karpowicz
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
Acceso en línea:https://doaj.org/article/ed03289e799f45ab8a7f60e215683623
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:ed03289e799f45ab8a7f60e215683623
record_format dspace
spelling oai:doaj.org-article:ed03289e799f45ab8a7f60e2156836232021-11-25T17:53:34ZThe Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element10.3390/ijms2222121221422-00671661-6596https://doaj.org/article/ed03289e799f45ab8a7f60e2156836232021-11-01T00:00:00Zhttps://www.mdpi.com/1422-0067/22/22/12122https://doaj.org/toc/1661-6596https://doaj.org/toc/1422-00676-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a significant role in chemical synthesis of modified peptides and in the polyamide synthetic fibers (nylon) industry. It is also often used as a linker in various biologically active structures. This review concentrates on the role of 6-aminohexanoic acid in the structure of various molecules.Agnieszka MarkowskaAdam Roman MarkowskiIwona Jarocka-KarpowiczMDPI AGarticle6-aminohexanoic acidantifibrynolyticslinkerBiology (General)QH301-705.5ChemistryQD1-999ENInternational Journal of Molecular Sciences, Vol 22, Iss 12122, p 12122 (2021)
institution DOAJ
collection DOAJ
language EN
topic 6-aminohexanoic acid
antifibrynolytics
linker
Biology (General)
QH301-705.5
Chemistry
QD1-999
spellingShingle 6-aminohexanoic acid
antifibrynolytics
linker
Biology (General)
QH301-705.5
Chemistry
QD1-999
Agnieszka Markowska
Adam Roman Markowski
Iwona Jarocka-Karpowicz
The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
description 6-aminohexanoic acid is an ω-amino acid with a hydrophobic, flexible structure. Although the ω-amino acid in question is mainly used clinically as an antifibrinolytic drug, other applications are also interesting and important. This synthetic lysine derivative, without an α-amino group, plays a significant role in chemical synthesis of modified peptides and in the polyamide synthetic fibers (nylon) industry. It is also often used as a linker in various biologically active structures. This review concentrates on the role of 6-aminohexanoic acid in the structure of various molecules.
format article
author Agnieszka Markowska
Adam Roman Markowski
Iwona Jarocka-Karpowicz
author_facet Agnieszka Markowska
Adam Roman Markowski
Iwona Jarocka-Karpowicz
author_sort Agnieszka Markowska
title The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
title_short The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
title_full The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
title_fullStr The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
title_full_unstemmed The Importance of 6-Aminohexanoic Acid as a Hydrophobic, Flexible Structural Element
title_sort importance of 6-aminohexanoic acid as a hydrophobic, flexible structural element
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/ed03289e799f45ab8a7f60e215683623
work_keys_str_mv AT agnieszkamarkowska theimportanceof6aminohexanoicacidasahydrophobicflexiblestructuralelement
AT adamromanmarkowski theimportanceof6aminohexanoicacidasahydrophobicflexiblestructuralelement
AT iwonajarockakarpowicz theimportanceof6aminohexanoicacidasahydrophobicflexiblestructuralelement
AT agnieszkamarkowska importanceof6aminohexanoicacidasahydrophobicflexiblestructuralelement
AT adamromanmarkowski importanceof6aminohexanoicacidasahydrophobicflexiblestructuralelement
AT iwonajarockakarpowicz importanceof6aminohexanoicacidasahydrophobicflexiblestructuralelement
_version_ 1718411896624775168