The role of innate APOBEC3G and adaptive AID immune responses in HLA-HIV/SIV immunized SHIV infected macaques.
The AID/APOBEC family (activation induced deaminase/apolipoprotein B mRNA editing cytokine deaminase) in B cells play important roles in adaptive and innate immunity. Whereas APOBEC3G has been studied in CD4+ T cells and myeloid cells its functional potential in B cells has received little attention...
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Autores principales: | Yufei Wang, Trevor Whittall, Durdana Rahman, Evelien M Bunnik, Robert Vaughan, Jørgen Schøller, Lesley A Bergmeier, David Montefiori, Mahavir Singh, Hanneke Schuitemaker, Thomas Lehner |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/ed06f658a4d04b789928d0a168119e7b |
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