Radiofrequency Denervation of Genicular Nerves for Advanced Knee Osteoarthritis Pain: A retrospective Observational Study

Background: Knee joint osteoarthritis is a degenerative disorder resulting in pain and disability. The treatment of knee osteoarthritis pain includes the use of oral analgesics, oral glucosamine and chondroitin sulfate, intra-articular steroid, and viscous supplementation, but with limited efficacy....

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Autores principales: Sandeep Khuba, Sanjay Kumar, Sujeet Gautam, Anil Agarwal, Chetna Shamshery, Keshav Garg, Rajput Kumar
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Publicado: Al-Azhar University, Faculty of Medicine (Damietta) 2021
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spelling oai:doaj.org-article:ed08d31dc47c43a9bd8240a3e710364d2021-12-02T14:49:25ZRadiofrequency Denervation of Genicular Nerves for Advanced Knee Osteoarthritis Pain: A retrospective Observational Study2636-41742682-378010.21608/ijma.2021.68924.1286https://doaj.org/article/ed08d31dc47c43a9bd8240a3e710364d2021-07-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_172331_86689e9eca58186c1a4c5bf82f77fc2d.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Knee joint osteoarthritis is a degenerative disorder resulting in pain and disability. The treatment of knee osteoarthritis pain includes the use of oral analgesics, oral glucosamine and chondroitin sulfate, intra-articular steroid, and viscous supplementation, but with limited efficacy. Aim of the work: This retrospective observational study aimed to evaluate the efficacy of radiofrequency thermocoagulation of genicular nerves for control of the pain of knee joint osteoarthritis. Material and methods: This study included patients with knee pain of Kellgren Lawrence grade 3 and 4 osteoarthritis who underwent radiofrequency neurotomy of the knee joint from July 2015 to July 2018. The 68 joints of 60 patients were evaluated for knee pain VAS score [0–10 mm], oxford knee score [12–60] and development of any adverse effect at pre and post-procedure at 1, 3, 6 and 12 months. Results: The mean± SD values of Visual analog scale [VAS] [0–10] for knee joint pain were 7.93±1.21, 3.38±1.59, 4.10±2.30, 4.90±1.88, and 5.80±1.71 at pre-procedure and at 1, 3, 6 and 12 months post-procedure. The mean ± SD values for Oxford Knee Score [OKS] [12–60] were 40.87±7.66, 23.90±5.60, 25.93±5.48, 27.93 ± 5.48, and 31.43±5.62 at pre-procedure and at 1, 3, 6 and 12 months post-procedure. One-way repeated measures of ANOVA test showed a significant decrease in VAS and OKS scores between pre and post-procedure at 1, 3, 6 and 12 months [p <0.001]. Conclusion: Radiofrequency thermocoagulation of genicular nerves provides significant pain relief and functional improvement in advanced knee joint osteoarthritis patients for a duration of one year.Sandeep KhubaSanjay KumarSujeet GautamAnil AgarwalChetna ShamsheryKeshav GargRajput KumarAl-Azhar University, Faculty of Medicine (Damietta)articleradiofrequency ablationlocal anaesthetic blockknee painultrasound guidedfluoroscope guidedMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 3, Pp 1576-1583 (2021)
institution DOAJ
collection DOAJ
language EN
topic radiofrequency ablation
local anaesthetic block
knee pain
ultrasound guided
fluoroscope guided
Medicine (General)
R5-920
spellingShingle radiofrequency ablation
local anaesthetic block
knee pain
ultrasound guided
fluoroscope guided
Medicine (General)
R5-920
Sandeep Khuba
Sanjay Kumar
Sujeet Gautam
Anil Agarwal
Chetna Shamshery
Keshav Garg
Rajput Kumar
Radiofrequency Denervation of Genicular Nerves for Advanced Knee Osteoarthritis Pain: A retrospective Observational Study
description Background: Knee joint osteoarthritis is a degenerative disorder resulting in pain and disability. The treatment of knee osteoarthritis pain includes the use of oral analgesics, oral glucosamine and chondroitin sulfate, intra-articular steroid, and viscous supplementation, but with limited efficacy. Aim of the work: This retrospective observational study aimed to evaluate the efficacy of radiofrequency thermocoagulation of genicular nerves for control of the pain of knee joint osteoarthritis. Material and methods: This study included patients with knee pain of Kellgren Lawrence grade 3 and 4 osteoarthritis who underwent radiofrequency neurotomy of the knee joint from July 2015 to July 2018. The 68 joints of 60 patients were evaluated for knee pain VAS score [0–10 mm], oxford knee score [12–60] and development of any adverse effect at pre and post-procedure at 1, 3, 6 and 12 months. Results: The mean± SD values of Visual analog scale [VAS] [0–10] for knee joint pain were 7.93±1.21, 3.38±1.59, 4.10±2.30, 4.90±1.88, and 5.80±1.71 at pre-procedure and at 1, 3, 6 and 12 months post-procedure. The mean ± SD values for Oxford Knee Score [OKS] [12–60] were 40.87±7.66, 23.90±5.60, 25.93±5.48, 27.93 ± 5.48, and 31.43±5.62 at pre-procedure and at 1, 3, 6 and 12 months post-procedure. One-way repeated measures of ANOVA test showed a significant decrease in VAS and OKS scores between pre and post-procedure at 1, 3, 6 and 12 months [p <0.001]. Conclusion: Radiofrequency thermocoagulation of genicular nerves provides significant pain relief and functional improvement in advanced knee joint osteoarthritis patients for a duration of one year.
format article
author Sandeep Khuba
Sanjay Kumar
Sujeet Gautam
Anil Agarwal
Chetna Shamshery
Keshav Garg
Rajput Kumar
author_facet Sandeep Khuba
Sanjay Kumar
Sujeet Gautam
Anil Agarwal
Chetna Shamshery
Keshav Garg
Rajput Kumar
author_sort Sandeep Khuba
title Radiofrequency Denervation of Genicular Nerves for Advanced Knee Osteoarthritis Pain: A retrospective Observational Study
title_short Radiofrequency Denervation of Genicular Nerves for Advanced Knee Osteoarthritis Pain: A retrospective Observational Study
title_full Radiofrequency Denervation of Genicular Nerves for Advanced Knee Osteoarthritis Pain: A retrospective Observational Study
title_fullStr Radiofrequency Denervation of Genicular Nerves for Advanced Knee Osteoarthritis Pain: A retrospective Observational Study
title_full_unstemmed Radiofrequency Denervation of Genicular Nerves for Advanced Knee Osteoarthritis Pain: A retrospective Observational Study
title_sort radiofrequency denervation of genicular nerves for advanced knee osteoarthritis pain: a retrospective observational study
publisher Al-Azhar University, Faculty of Medicine (Damietta)
publishDate 2021
url https://doaj.org/article/ed08d31dc47c43a9bd8240a3e710364d
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AT sujeetgautam radiofrequencydenervationofgenicularnervesforadvancedkneeosteoarthritispainaretrospectiveobservationalstudy
AT anilagarwal radiofrequencydenervationofgenicularnervesforadvancedkneeosteoarthritispainaretrospectiveobservationalstudy
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