Succession of oral microbiota community as a tool to estimate postmortem interval

Abstract The establishment of postmortem interval is one of the most important aspects of forensic expertise. Microbes may provide a novel way to estimate the postmortem intervals in order to avoid many of these limitations. The oral cavity harbors one of the most diverse microbiomes that play a key...

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Autores principales:	Kaikai Dong, Ye Xin, Fangqi Cao, Zhiwei Huang, Jing Sun, Min Peng, Wenbin Liu, Ping Shi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ed0cb0b37b034bb19c80526f473ed18e
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spelling	oai:doaj.org-article:ed0cb0b37b034bb19c80526f473ed18e2021-12-02T16:07:53ZSuccession of oral microbiota community as a tool to estimate postmortem interval10.1038/s41598-019-49338-z2045-2322https://doaj.org/article/ed0cb0b37b034bb19c80526f473ed18e2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-49338-zhttps://doaj.org/toc/2045-2322Abstract The establishment of postmortem interval is one of the most important aspects of forensic expertise. Microbes may provide a novel way to estimate the postmortem intervals in order to avoid many of these limitations. The oral cavity harbors one of the most diverse microbiomes that play a key role in the decomposition of corpses. In this study, the oral bacterial community showed obvious changes in relative abundance during the process of mice decomposition. Meanwhile, at different taxonomic levels, specific bacteria were found to be significantly correlated with the postmortem interval. Linear regression models between relative abundance and the postmortem interval were constructed. Among these species, Gamma-proteobacteria and Proteus were the best ones that can be used to infer the postmortem interval, especially late postmortem interval. Therefore, we suggest that succession of oral microbial community can be developed as a forensic tool for estimating the postmortem interval.Kaikai DongYe XinFangqi CaoZhiwei HuangJing SunMin PengWenbin LiuPing ShiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kaikai Dong Ye Xin Fangqi Cao Zhiwei Huang Jing Sun Min Peng Wenbin Liu Ping Shi Succession of oral microbiota community as a tool to estimate postmortem interval
description	Abstract The establishment of postmortem interval is one of the most important aspects of forensic expertise. Microbes may provide a novel way to estimate the postmortem intervals in order to avoid many of these limitations. The oral cavity harbors one of the most diverse microbiomes that play a key role in the decomposition of corpses. In this study, the oral bacterial community showed obvious changes in relative abundance during the process of mice decomposition. Meanwhile, at different taxonomic levels, specific bacteria were found to be significantly correlated with the postmortem interval. Linear regression models between relative abundance and the postmortem interval were constructed. Among these species, Gamma-proteobacteria and Proteus were the best ones that can be used to infer the postmortem interval, especially late postmortem interval. Therefore, we suggest that succession of oral microbial community can be developed as a forensic tool for estimating the postmortem interval.
format	article
author	Kaikai Dong Ye Xin Fangqi Cao Zhiwei Huang Jing Sun Min Peng Wenbin Liu Ping Shi
author_facet	Kaikai Dong Ye Xin Fangqi Cao Zhiwei Huang Jing Sun Min Peng Wenbin Liu Ping Shi
author_sort	Kaikai Dong
title	Succession of oral microbiota community as a tool to estimate postmortem interval
title_short	Succession of oral microbiota community as a tool to estimate postmortem interval
title_full	Succession of oral microbiota community as a tool to estimate postmortem interval
title_fullStr	Succession of oral microbiota community as a tool to estimate postmortem interval
title_full_unstemmed	Succession of oral microbiota community as a tool to estimate postmortem interval
title_sort	succession of oral microbiota community as a tool to estimate postmortem interval
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ed0cb0b37b034bb19c80526f473ed18e
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_version_	1718384690886344704

Succession of oral microbiota community as a tool to estimate postmortem interval

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