Anti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice

Background and objective: Portulaca oleracea (PO) overgrows in the different parts of Iran, that is used there as both a salad green and a medicinal plant. In previous studies, a 10% ethanolic extracts of the aerial parts (Leaf and stem) of PO showed anti-nociceptive activity in mice and rats. This...

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Autores principales:	H Miladi Gorgi, A Rashidi Pour, R Ghorbani
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2005
Materias:	portulaca oleracea (seed) anti-nociception tail flick Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/ed1e8824640a45d3be2f37f3a09979b6
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spelling	oai:doaj.org-article:ed1e8824640a45d3be2f37f3a09979b62021-11-10T09:14:41ZAnti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice1561-41072251-7170https://doaj.org/article/ed1e8824640a45d3be2f37f3a09979b62005-07-01T00:00:00Zhttp://jbums.org/article-1-2614-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and objective: Portulaca oleracea (PO) overgrows in the different parts of Iran, that is used there as both a salad green and a medicinal plant. In previous studies, a 10% ethanolic extracts of the aerial parts (Leaf and stem) of PO showed anti-nociceptive activity in mice and rats. This study was designed to evaluate anti-nociceptive effects of different doses of the aqueous decoction extracts of PO (Seed). Methods: In this study, 65 male mice (25-30 gr) in model tail flick were used. Different doses of the extract 25, 50, 75, 100 mg/kg (IP) were injected to the separated groups of four (Test group) and water (10 ml/kg-IP) was injected to the one control group. The anti-nociceptive effect was determined 15 and 30 min after injection (N=15 mice for pilot study). Findings: The results showed that there was a significant difference between two groups (P<0.05), but the animals of test groups did not show significant difference in different doses and time. Conclusion: It is concluded that the aqueous extract of PO has anti-nociceptive activity, which is not related to dose and time.H Miladi GorgiA Rashidi PourR GhorbaniBabol University of Medical Sciencesarticleportulaca oleracea (seed)anti-nociceptiontail flickMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 7, Iss 3, Pp 7-11 (2005)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	portulaca oleracea (seed) anti-nociception tail flick Medicine R Medicine (General) R5-920
spellingShingle	portulaca oleracea (seed) anti-nociception tail flick Medicine R Medicine (General) R5-920 H Miladi Gorgi A Rashidi Pour R Ghorbani Anti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice
description	Background and objective: Portulaca oleracea (PO) overgrows in the different parts of Iran, that is used there as both a salad green and a medicinal plant. In previous studies, a 10% ethanolic extracts of the aerial parts (Leaf and stem) of PO showed anti-nociceptive activity in mice and rats. This study was designed to evaluate anti-nociceptive effects of different doses of the aqueous decoction extracts of PO (Seed). Methods: In this study, 65 male mice (25-30 gr) in model tail flick were used. Different doses of the extract 25, 50, 75, 100 mg/kg (IP) were injected to the separated groups of four (Test group) and water (10 ml/kg-IP) was injected to the one control group. The anti-nociceptive effect was determined 15 and 30 min after injection (N=15 mice for pilot study). Findings: The results showed that there was a significant difference between two groups (P<0.05), but the animals of test groups did not show significant difference in different doses and time. Conclusion: It is concluded that the aqueous extract of PO has anti-nociceptive activity, which is not related to dose and time.
format	article
author	H Miladi Gorgi A Rashidi Pour R Ghorbani
author_facet	H Miladi Gorgi A Rashidi Pour R Ghorbani
author_sort	H Miladi Gorgi
title	Anti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice
title_short	Anti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice
title_full	Anti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice
title_fullStr	Anti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice
title_full_unstemmed	Anti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice
title_sort	anti-nociceptive effects of the aqueous extracts of portulaca oleracea seeds in mice
publisher	Babol University of Medical Sciences
publishDate	2005
url	https://doaj.org/article/ed1e8824640a45d3be2f37f3a09979b6
work_keys_str_mv	AT hmiladigorgi antinociceptiveeffectsoftheaqueousextractsofportulacaoleraceaseedsinmice AT arashidipour antinociceptiveeffectsoftheaqueousextractsofportulacaoleraceaseedsinmice AT rghorbani antinociceptiveeffectsoftheaqueousextractsofportulacaoleraceaseedsinmice
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Anti-nociceptive effects of the aqueous extracts of Portulaca Oleracea seeds in mice

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