The first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure
Linezolid provides high rates of the clinical cure and microbiological success in complicated infections due to Enterococcus spp., including vancomycin-resistant Enterococcus faecium. However, the emergence of resistance during linezolid treatment has been reported for clinical strains of Enterococc...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2014
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oai:doaj.org-article:ed24107eac944273b47d31fb5dc70a4b2021-12-02T17:05:52ZThe first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure2231-07702249-446410.4103/2231-0770.127416https://doaj.org/article/ed24107eac944273b47d31fb5dc70a4b2014-01-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.127416https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Linezolid provides high rates of the clinical cure and microbiological success in complicated infections due to Enterococcus spp., including vancomycin-resistant Enterococcus faecium. However, the emergence of resistance during linezolid treatment has been reported for clinical strains of Enterococcus, which is alarming given the fact that, this leaves the clinician with very few treatment options. We report the first case of linezolid resistant Enterococcus faecium from India, which was isolated from the blood culture of a hypoglycemic encephalopathy patient. There have been previous reports of linezolid resistant enterococci from different parts of the world, with minimum inhibitory concentration (MIC) ranging from 16 to 64 μg/mL and most of them were associated with vancomycin resistance but the isolate reported over here had an MIC of 1024 μg/mL and interestingly was sensitive to vancomycin.Simit KumarMaitreyi BandyoapdhyayMitali ChatterjeePrabir MukhopadhyaySumon PoddarParthajit BanerjeeThieme Medical and Scientific Publishers Pvt. Ltd.articleenterococcus faeciumlinezolid resistanttesting methods for detecting linezolid minimum inhibitory concentrationMedicineRENAvicenna Journal of Medicine, Vol 04, Iss 01, Pp 13-16 (2014) |
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enterococcus faecium linezolid resistant testing methods for detecting linezolid minimum inhibitory concentration Medicine R |
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enterococcus faecium linezolid resistant testing methods for detecting linezolid minimum inhibitory concentration Medicine R Simit Kumar Maitreyi Bandyoapdhyay Mitali Chatterjee Prabir Mukhopadhyay Sumon Poddar Parthajit Banerjee The first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure |
description |
Linezolid provides high rates of the clinical cure and microbiological success in complicated infections due to Enterococcus spp., including vancomycin-resistant Enterococcus faecium. However, the emergence of resistance during linezolid treatment has been reported for clinical strains of Enterococcus, which is alarming given the fact that, this leaves the clinician with very few treatment options. We report the first case of linezolid resistant Enterococcus faecium from India, which was isolated from the blood culture of a hypoglycemic encephalopathy patient. There have been previous reports of linezolid resistant enterococci from different parts of the world, with minimum inhibitory concentration (MIC) ranging from 16 to 64 μg/mL and most of them were associated with vancomycin resistance but the isolate reported over here had an MIC of 1024 μg/mL and interestingly was sensitive to vancomycin. |
format |
article |
author |
Simit Kumar Maitreyi Bandyoapdhyay Mitali Chatterjee Prabir Mukhopadhyay Sumon Poddar Parthajit Banerjee |
author_facet |
Simit Kumar Maitreyi Bandyoapdhyay Mitali Chatterjee Prabir Mukhopadhyay Sumon Poddar Parthajit Banerjee |
author_sort |
Simit Kumar |
title |
The first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure |
title_short |
The first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure |
title_full |
The first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure |
title_fullStr |
The first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure |
title_full_unstemmed |
The first linezolid-resistant Enterococcus faecium in India: High level resistance in a patient with no previous antibiotic exposure |
title_sort |
first linezolid-resistant enterococcus faecium in india: high level resistance in a patient with no previous antibiotic exposure |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
publishDate |
2014 |
url |
https://doaj.org/article/ed24107eac944273b47d31fb5dc70a4b |
work_keys_str_mv |
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