Candida albicans keratitis in an immunocompromised patient
H Mohammed J Hassan1, Theocharis Papanikolaou2, Georgios Mariatos1, Amany Hammad3, Hala Hassan41Ophthalmology Department, Barnsley Hospital NHS Foundation Trust, South Yorkshire, England, UK; 2Ophthalmology Department, Cambridge University Hospitals NHS Foundation Trust, England, UK; 3Ophthalmology...
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Dove Medical Press
2010
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oai:doaj.org-article:ed2de1872f774fee9abc88f3840a51a12021-12-02T04:35:55ZCandida albicans keratitis in an immunocompromised patient1177-54671177-5483https://doaj.org/article/ed2de1872f774fee9abc88f3840a51a12010-10-01T00:00:00Zhttp://www.dovepress.com/candida-albicans-keratitis-in-an-immunocompromised-patient-a5513https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483H Mohammed J Hassan1, Theocharis Papanikolaou2, Georgios Mariatos1, Amany Hammad3, Hala Hassan41Ophthalmology Department, Barnsley Hospital NHS Foundation Trust, South Yorkshire, England, UK; 2Ophthalmology Department, Cambridge University Hospitals NHS Foundation Trust, England, UK; 3Ophthalmology Department, Rotherham Hospital NHS Foundation Trust, England, UK; 4Corneal and External Disease Service, Moorfields Eye Hospital NHS Foundation Trust, London, England, UKPurpose: When investigating a case of unexplained corneal ulceration, we need to think of fungal infection and any predisposing factors.Methods: A case study of a corneal ulceration in a patient who was HIV positive with a devastating visual outcome.Results: Therapeutic corneal graft was necessary due to corneal perforation. Immunocompromised state of patient was retrospectively diagnosed.Conclusions: Candida albicans keratitis is an opportunistic infection of a compromised cornea, and sometimes unknowingly compromised host, which can be initially misdiagnosed. Despite intensive antifungal therapy, occasionally patients require corneal grafting to improve vision, and before it is possible to establish an accurate diagnosis.Keywords: fungal keratitis, corneal perforation, keratoplasty, human immunodeficiency virus, HIV H Mohammed J HassanTheocharis PapanikolaouGeorgios Mariatoset alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 1211-1215 (2010) |
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Ophthalmology RE1-994 H Mohammed J Hassan Theocharis Papanikolaou Georgios Mariatos et al Candida albicans keratitis in an immunocompromised patient |
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H Mohammed J Hassan1, Theocharis Papanikolaou2, Georgios Mariatos1, Amany Hammad3, Hala Hassan41Ophthalmology Department, Barnsley Hospital NHS Foundation Trust, South Yorkshire, England, UK; 2Ophthalmology Department, Cambridge University Hospitals NHS Foundation Trust, England, UK; 3Ophthalmology Department, Rotherham Hospital NHS Foundation Trust, England, UK; 4Corneal and External Disease Service, Moorfields Eye Hospital NHS Foundation Trust, London, England, UKPurpose: When investigating a case of unexplained corneal ulceration, we need to think of fungal infection and any predisposing factors.Methods: A case study of a corneal ulceration in a patient who was HIV positive with a devastating visual outcome.Results: Therapeutic corneal graft was necessary due to corneal perforation. Immunocompromised state of patient was retrospectively diagnosed.Conclusions: Candida albicans keratitis is an opportunistic infection of a compromised cornea, and sometimes unknowingly compromised host, which can be initially misdiagnosed. Despite intensive antifungal therapy, occasionally patients require corneal grafting to improve vision, and before it is possible to establish an accurate diagnosis.Keywords: fungal keratitis, corneal perforation, keratoplasty, human immunodeficiency virus, HIV |
format |
article |
author |
H Mohammed J Hassan Theocharis Papanikolaou Georgios Mariatos et al |
author_facet |
H Mohammed J Hassan Theocharis Papanikolaou Georgios Mariatos et al |
author_sort |
H Mohammed J Hassan |
title |
Candida albicans keratitis in an immunocompromised patient |
title_short |
Candida albicans keratitis in an immunocompromised patient |
title_full |
Candida albicans keratitis in an immunocompromised patient |
title_fullStr |
Candida albicans keratitis in an immunocompromised patient |
title_full_unstemmed |
Candida albicans keratitis in an immunocompromised patient |
title_sort |
candida albicans keratitis in an immunocompromised patient |
publisher |
Dove Medical Press |
publishDate |
2010 |
url |
https://doaj.org/article/ed2de1872f774fee9abc88f3840a51a1 |
work_keys_str_mv |
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_version_ |
1718401160364163072 |