Alterations of DNA methylation during adipogenesis differentiation of mesenchymal stem cells isolated from adipose tissue of patients with obesity is associated with type 2 diabetes

Alterations of DNA methylation during adipogenesis differentiation of mesenchymal stem cells isolated from adipose tissue of patients with obesity is associated with type 2 diabetes

Adipogenesis regulation is crucial for mature adipocyte function. In obesity, a major driver of type 2 diabetes (T2D), this process is disrupted and remains poorly characterized. Here we identified altered DNA methylation profiles in diabetic obese patients, during three adipocytes differentiation s...

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Main Authors: Elaheh Mirzaeicheshmeh, Carlos Zerrweck, Federico Centeno-Cruz, Paulina Baca-Peynado, Angélica Martinez-Hernandez, Humberto García-Ortiz, Cecilia Contreras-Cubas, María Guadalupe Salas-Martínez, Yolanda Saldaña-Alvarez, Elvia C. Mendoza-Caamal, Francisco Barajas-Olmos, Lorena Orozco
Format: article
Language:EN
Published: Taylor & Francis Group 2021
Subjects:
adipogenesis
type 2 diabetes
obesity
dna methylation
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Cytology
QH573-671
Physiology
QP1-981
Online Access:https://doaj.org/article/ed378195d09546b59a8bcf02ff88a8be
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https://doaj.org/article/ed378195d09546b59a8bcf02ff88a8be

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