Alterations of DNA methylation during adipogenesis differentiation of mesenchymal stem cells isolated from adipose tissue of patients with obesity is associated with type 2 diabetes

Adipogenesis regulation is crucial for mature adipocyte function. In obesity, a major driver of type 2 diabetes (T2D), this process is disrupted and remains poorly characterized. Here we identified altered DNA methylation profiles in diabetic obese patients, during three adipocytes differentiation s...

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Auteurs principaux:	Elaheh Mirzaeicheshmeh, Carlos Zerrweck, Federico Centeno-Cruz, Paulina Baca-Peynado, Angélica Martinez-Hernandez, Humberto García-Ortiz, Cecilia Contreras-Cubas, María Guadalupe Salas-Martínez, Yolanda Saldaña-Alvarez, Elvia C. Mendoza-Caamal, Francisco Barajas-Olmos, Lorena Orozco
Format:	article
Langue:	EN
Publié:	Taylor & Francis Group 2021
Sujets:	adipogenesis type 2 diabetes obesity dna methylation Diseases of the endocrine glands. Clinical endocrinology RC648-665 Cytology QH573-671 Physiology QP1-981
Accès en ligne:	https://doaj.org/article/ed378195d09546b59a8bcf02ff88a8be
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Alterations of DNA methylation during adipogenesis differentiation of mesenchymal stem cells isolated from adipose tissue of patients with obesity is associated with type 2 diabetes

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